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New research by a team of Indiana University School of Medicine scientists and their collaborators has uncovered a novel vulnerability in prostate cancer animal models that starves prostate tumors of critical nutrients and stunts their growth, which could lead to the development of new treatments for the deadly disease.

Led by IU School of Medicine’s Kirk Staschke, Ph.D., assistant research professor of biochemistry and molecular biology, and Ronald C. Wek, Ph.D., Showalter Professor of Biochemistry, the study was recently published in Science Signaling.

Prostate cancer is a leading cause of cancer deaths in American men...

Light-emitting diodes (LEDs), semiconductor-based devices that emit light when an electric current flows through them, are key building blocks of numerous electronic devices. LEDs are used to light up smartphone, computer, and TV displays, as well as light sources for indoor and outdoor environments.

Past studies consistently observed a decline in the performance and efficiency of LED devices based on two-dimensional (2D) materials at high current densities. This loss of efficiency at high current densities has been linked to high levels of interaction between excitons, which cause a process known as exciton-exciton annihilation (EEA).

Essentially, the properties of some 2D materials...

Researchers at Baylor College of Medicine, Stanford University School of Medicine and collaborating institutions report in the journal Cell the discovery of BHB-Phe, a novel compound produced by the body that regulates appetite and body weight through interactions with neurons in the brain.

Until now, BHB has been known as a compound produced by the liver to be used as fuel. However, in recent years, scientists have found that BHB increases in the body after fasting or exercise, prompting interest in investigating potential beneficial applications in obesity and diabetes.

In the current study, the team at Stanford University led by co-corresponding author Dr. Jonathan Z. Long, associate professor of pathology, discovered that BHB also participates in another metabolic pathway...

An international research team has for the first time designed realistic photonic time crystals–exotic materials that exponentially amplify light. The breakthrough opens up exciting possibilities across fields such as communication, imaging and sensing by laying the foundations for faster and more compact lasers, sensors and other optical devices.

“This work could lead to the first experimental realization of photonic time crystals, propelling them into practical applications and potentially transforming industr...