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Engineers grow 3D bioprinted blood vessel

collage of four images demonstrating the process used in the lab
These images depict the method used to fabricate the 3D bioprinted vascular model with native endothelial and vascular smooth muscle cells.

Courtesy of Akhilesh Gaharwar

Vascular diseases such as aneurysms, peripheral artery disease and clots inside blood vessels account for 31% of global deaths. Despite this clinical burden, cardiovascular drug advancements have slowed over the past 20 years. The decrease in cardiovascular therapeutic development is attributed to the lack of efficiency in converting possible treatments into approved methods, specifically due to the discrepancy between studies that take place outside the body compared to inside.

Researchers at Texas A&M University aim to remodel current methodologies to minimize this gap and improve the translatability of these techn...

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Cracking a Mystery of Massive Black Holes and Quasars with Supercomputer Simulations

Distribution of gas across scales, with the gas density increasing from purple to yellow. The top left panel shows a large region containing tens of galaxies (6 million light-years across). Subsequent panels zoom in progressively into the nuclear region of the most massive galaxy and down to the vicinity of the central supermassive black hole. Gas clumps and filaments fall from the inner edge of the central cavity occasionally feeding the black hole. Credit: Anglés-Alcázar et al. 2021, ApJ, 917, 53.
Distribution of gas across scales, with the gas density increasing from purple to yellow. The top left panel shows a large region containing tens of galaxies (6 million light-years across). Subsequent panels zoom in progressively into the nuclear region of the most massive galaxy and down to the vicinity of the central supermassive black hole. Gas clumps and filaments fall from the inner edge of the central cavity occasionally feeding the black hole.
(Credit: Anglés-Alcázar et al. 2021, ApJ, 917, 53.)

Cracking a mystery of massive black holes and quasars with supercomputer simulations. At the center of galaxies, like our own Milky Way, lie massive black holes surrounded by spinning gas...

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Brain Cholesterol Regulates Alzheimer’s Plaques, study reveals

Brain cholesterol regulates Alzheimer's plaques, study reveals
Depletion of cholesterol in astrocytes (right) directly removes amyloid plaques and phosphorylated Tau (left, orange clusters) in an Alzheimer’s mouse model. Credit: Scott Hansen Lab, Scripps Research, Jupiter, Florida.

Advanced imaging technique shows how cholesterol regulates production of Alzheimer’s-associated amyloid beta protein in a type of brain cell.

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer’s-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

Appearing on line Thursday ahead of print in the Aug...

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Novel technique seamlessly converts Ammonia to ‘Green’ Hydrogen

A research team, led by Professor Guntae Kim in the School of Energy and Chemical Engineering at UNIST has announced a breakthrough in technology that efficiently converts liquid ammonia into hydrogen. Their findings have also attracted significant attention from academic research communities owing to its new analysis protocol, capable of finding optimal process environments.

In this study, the research team succeeded in producing green hydrogen (H2) in large quantities with a purity of nearly 100 percent by decomposing liquid ammonia (NH3) into electricity. Besides, according to the research team, such method consumed three times less power than hydrogen made using electrolysis of water.

Ammonia has emerged as an attractive potential hydrogen carrier due to its extremely high e...

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