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Engineers design nanoparticles that stimulate the immune system, helping it to attack tumors. MIT engineers have now come up with a way to boost the effectiveness of one type of cancer immunotherapy. They showed that if they treated mice with existing drugs called checkpoint inhibitors, along with new nanoparticles that further stimulate the immune system, the therapy became more powerful than checkpoint inhibitors given alone. This approach could allow cancer immunotherapy to benefit a greater percentage of patients, the researchers say.

“These ...

Researchers have developed a new easy-to-use smart optical film technology that allows smart window devices to autonomously switch between transparent and opaque states in response to the surrounding light conditions.

The proposed 3D hybrid nanocomposite film with a highly periodic network structure has empirically demonstrated its high speed and performance, enabling the smart window to quantify and self-regulate its high-contrast optical transmittance. As a proof of concept, a mobile-app-enabled smart window device for Internet of Things (IoT) applications has been realized using the proposed smart optical film with successful expansion to the 3-by-3-inch scale...

Brown dwarfs are the middle child of astronomy, too big to be a planet yet not big enough to be a star. Like their stellar siblings, these objects form from the gravitational collapse of gas and dust. But rather than condensing into a star’s fiery hot nuclear core, brown dwarfs find a more zen-like equilibrium, somehow reaching a stable, milder state compared to fusion-powered stars.

Brown dwarfs are considered to be the mis...

New research conducted by the University of Liverpool and AKL Research and Development Ltd (AKLRD), published in Inflammopharmacology, highlights the potential benefits of a new drug treatment on the human body’s immune response in inflammation.

In a number of inflammatory conditions, such as osteoarthritis, rheumatoid arthritis and, more recently, COVID-19, major complications and extensive tissue damage can occur when the immune system becomes excessively and uncontrollably activated...