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Non-Invasive Prenatal Genetic test is accurate 5 weeks into Pregnancy

Study reveals non-invasive prenatal genetic test is accurate five weeks into pregnancy

Comparison of approaches to obtain fetal DNA in ongoing pregnancies, including amniocentesis, chorionic villous sampling (CVS), cell-free fetal DNA, and trophoblast retrieval isolation from the cervix (TRIC). Sources of fetal DNA throughout early pregnancy are illustrated according to their accessibility during gestation. Credit: Jain et al., Science Translational Medicine (2016)

The latest developments in prenatal technology conceived by scientists at the Wayne State University School of Medicine that make it possible to test for genetic disorders a little more than 1 month into pregnancy were revealed this week...

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How your Body Transports Zinc to protect your Health

Graphical abstract: Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins

Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins… The major site in both HSA and ESA has tetrahedral geometry and comprises three protein ligands from the sidechains of His67, His247 and Asp249 and a water molecule. Isothermal titration calorimetric studies of a HSA H67A mutant confirm this to be the highest affinity Zn2+ site. Furthermore, analysis of Zn2+ binding to HSA and ESA proved the presence of secondary sites with 20–50-fold weaker affinities, which may become of importance under particular physiological conditions. Both calorimetry and crystallography suggest that ESA possesses an additional site compared to HSA, involving Glu153, His157 and His288. The His157 residue is replaced by Phe in HSA, incapable of metal coordination...

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Bioelectronics at the Speed of Life

DanielSimon and Theresia Arbring Sjöström. Credit: Image courtesy of Linköping Universitet

DanielSimon and Theresia Arbring Sjöström. Credit: Image courtesy of Linköping Universitet

With a microfabricated ion pump built from organic electronic components, ions can be sent to nerve or muscle cells at the speed of the nervous system and with a precision of a single cell. “Now we can start to develop components that speak the body’s own language,” says Daniel Simon, Laboratory of Organic Electronics, Linköping University. Certain substances, such as GABA, are important signal substances throughout the CNS. 18 months ago, researchers at the Laboratory of Organic Electronics demonstrated an ion pump which researchers at the Karolinska Institutet could use to reduce the sensation of pain in awake, freely-moving rats. The ion pump delivered GABA directly to the rat´s spinal cord.

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Ultra-fast 2D and 3D Printing: Major Advance in field of High-Speed Beam-Scanning devices

Illustration of a KTN crystal operating under different phases. Credit: Penn State

Illustration of a KTN crystal operating under different phases. Credit: Penn State

A major technological advance in the field of high-speed beam-scanning devices has increased the speed of 2D and 3D printing by up to 1000 times, according to researchers in Penn State’s College of Engineering. Using a space-charge-controlled KTN beam deflector – a kind of crystal made of potassium tantalate and potassium niobate – with a large electro-optic effect, researchers have found that scanning at a much higher speed is possible.

“Basically, when the crystal materials are applied to an electric field, they generate uniform reflecting distributions, that can deflect an incoming light beam,” said Prof. Shizhuo Yin...

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