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Breakthrough in Production of Dopamine Neurons for Parkinson’s disease

breakthrough-in-production-of-dopamine-neurons-for-parkinsons-disease-science_2016-10-30_13-09-34

The first transplantation of stem cells in patients with Parkinson’s disease is almost within reach. However, it remains a challenge for researchers to control stem cells accurately in the lab in order to achieve successful and functional stem cell therapies for patients. “In our preclinical assessments of stem cell-derived dopamine neurons we noticed that the outcome in animal models varied dramatically, even though the cells were very similar at the time of transplantation. This has been frustrating and puzzling, and has significantly delayed the establishment of clinical cell production protocols,” says Malin Parmar, who led the study conducted at Lund University as part of the EU network NeuroStemcellRepair.

The Lund experiments use modern global gene expression studies to better unde...

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When it comes to Atomic-Scale Manufacturing, less really is more

Robert Wolkow, University of Alberta physics professor and the Principal Research Officer at Canada's National Institute for Nanotechnology, has developed a technique to switch a single-atom channel. Credit: John Ulan

Robert Wolkow, University of Alberta physics professor and the Principal Research Officer at Canada’s National Institute for Nanotechnology, has developed a technique to switch a single-atom channel. Credit: John Ulan

Robert Wolkow, a pioneer in atomic-scale science with a Guinness World Record to boot (for a needle with a single atom at the point), and Max Plank Institute in Hamburg, have just released findings that detail how to create atomic switches for electricity, many times smaller than what is currently used. With applications for practical systems like silicon semi-conductor electronics, it means smaller, more efficient, more energy-conserving computers, as just one example of the technology revolution that is unfolding right before our very eyes (if you can squint that hard).

“Th...

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Ripples in Space Key to Understanding Cosmic Rays

Ripples in space shocks key to understanding cosmic rays

The MMS satellites encounter a shock wave that forms when a fast wind of charged particles from the Sun slams into Earth’s magnetic field. Credit: APS/Carin Cain

In a new study researchers at the Swedish Institute of Space Physics have used measurements from NASA’s MMS (Magnetospheric MultiScale) satellites to reveal that there are ripples, or surface waves, moving along the surface of shocks in space. Such ripples in shocks can affect how plasma is heated and are potential sites of particle acceleration.

Most visible matter in the Universe consists of ionized gas known as plasma. Shock waves in plasmas form around planets, stars and supernovas. Shocks in supernova explosions are thought to be the main source of cosmic rays – very high energy charged particles from space...

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DNA-based Single-Electron Electronic Devices created

Gold nanoparticles are attached directly within the aqueous solution onto a DNA structure. The whole process is based on DNA self-assembly, and yields countless of structures within a single patch. Credit: Image courtesy of Academy of Finland

Gold nanoparticles are attached directly within the aqueous solution onto a DNA structure. The whole process is based on DNA self-assembly, and yields countless of structures within a single patch. Credit: Image courtesy of Academy of Finland

Researchers at the Nanoscience Center (NSC) of the University of Jyväskylä and BioMediTech (BMT) of the University of Tampere have now demonstrated a method to fabricate electronic devices by using DNA. The DNA itself has no part in the electrical function, but acts as a scaffold for forming a linear, pearl-necklace-like nanostructure consisting of 3 gold nanoparticles.

The nature of electrical conduction in nanoscale materials can differ vastly from regular, macroscale metallic structures, which have countless free electrons forming the current, th...

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