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New Treatment leaves Liver Cancer cells in Limbo

Stuck in senescence, this cell can no longer grow or divide. The Arid1b protein (green) induces this state by regulating the expression of specific genes. In contrast other regions of the DNA (blue) contain genes that are not bound by Arid1b and are not expressed (red). Credit: MRC CSC

Stuck in senescence, this cell can no longer grow or divide. The Arid1b protein (green) induces this state by regulating the expression of specific genes. In contrast other regions of the DNA (blue) contain genes that are not bound by Arid1b and are not expressed (red). Credit: MRC CSC

Scientists have shown that a mutation in gene Arid1b can cause liver cancer. The gene normally protects against cancer by limiting cell growth, but when mutated it allows cells to grow uncontrollably. The researchers have shown that two existing drugs can halt this growth in human cells. This points to a new approach to treating liver cancer. These early results could be translated into a treatment relatively quickly. This is because the drugs are already used to treat other types of cancer...

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Physicists Induce Superconductivity in Non-Superconducting materials

Paul C.W. Chu. Credit: University of Houston

Paul C.W. Chu. Credit: University of Houston

Researchers at the University of Houston have reported a new method for inducing superconductivity in non-superconducting materials, demonstrating a concept proposed decades ago but never proven.The technique can also be used to boost the efficiency of known superconducting materials, suggesting a new way to advance the commercial viability of superconductors, said Paul C.W. Chu, TcSUH.

“Superconductivity is used in many things, of which MRI is perhaps the best known,” said Chu, the physicist who holds the TLL Temple Chair of Science at UH. But the technology used in health care, utilities and other fields remains expensive, in part because it requires expensive cooling...

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Team Heats up Exotic Topological Insulators

animation of topological insulator

This topological insulator, doped with chromium (Cr) atoms, conducts electricity on its surface and possesses desirable magnetic properties at a higher range of temperatures than before when sandwiched between magnetic materials known as ferromagnets. Credit: Natasha Hanacek/NIST

Traditional semiconductors like silicon are releasing their last new lines. Exotic materials called topological insulators (TIs) are on their way in. And when it comes to cool, nitrogen is the new helium. This was clearly on display in a novel experiment at the National Institute of Standards and Technology (NIST) that was performed by a multi-institutional collaboration including UCLA, NIST and the Beijing Institute of Technology in China.

Topological insulators are a new class of materials that were discovered l...

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Hypervariable Galactic Nuclei

A photo of the PanSTARRS (Panoramic Survey Telescope & Rapid Response System) telescope in Hawaii. Astronomers have used a sky survey from this facility to identify a of blue, hypervariable galaxies; the origin of the variability is uncertain but might in some cases be due to microlensing. Credit: PanSTARRS

A photo of the PanSTARRS (Panoramic Survey Telescope & Rapid Response System) telescope in Hawaii. Astronomers have used a sky survey from this facility to identify a class of blue, hypervariable galaxies; the origin of the variability is uncertain but might in some cases be due to microlensing. Credit: PanSTARRS

Extreme variability in the intensity of the optical light of galaxies, by factors of 2 or more, is of great interest to astronomers. It can flag the presence of rare types of supernovae, for example, or spot sudden accretion activity around quiescent black holes or around the supermassive black hole at the galaxy’s nucleus. In recent years systematic searches for such variability have been made using instruments that can survey wide swaths of the sky...

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