Eating oily fish twice a week can protect your eyesight a study has revealed
In middle-aged and older individuals with type 2 diabetes, intake of at least 500 mg/d of dietary long-chain ω-3 polyunsaturated fatty acids, easily achievable with 2 weekly servings of oily fish, was associated with a decreased risk of sight-threatening diabetic retinopathy, according to a study published online by JAMA Ophthalmology.
Given the economic and societal burden of DR, developing effective strategies to prevent or at least delay its onset is a major public health issue. The retina is rich in long-chain ω-3 polyunsaturated fatty acids (LCω3PUFAs). Experimental models support dietary LCω3PUFA protection against DR, but clinical data are lacking. Aleix Sala-Vila, D.Pharm., Ph.D., of the Lipid Clinic, Barcelona et al conducted a prospective study within the randomized clinical trial Prevencion con Dieta Mediterranea (PREDIMED), testing Mediterranean diets supplemented with extra virgin olive oil or nuts vs a control diet for primary cardiovascular prevention. The trial was conducted in primary health care centers in Spain. From 2003 to 2009, 3,614 individuals age 55 to 80 years with a previous diagnosis of type 2 diabetes were recruited. Full data were available for 3,482 participants (48 percent men; average age 67 years). Meeting the dietary LCω3PUFA recommendation of at least 500 mg/d for primary cardiovascular prevention was assessed by a validated food-frequency questionnaire.
Diabetic retinopathy
A total of 2,611 (75%) met the target LCω3PUFA recommendation. During a median follow-up of 6 years, incident DR was diagnosed in 69 of the study participants. After adjusting for age, sex, intervention group, and lifestyle and clinical variables, participants meeting the LCω3PUFA recommendation at baseline (500 mg/d or greater) compared with those not fulfilling this recommendation (less than 500 mg/d) showed a 48% relatively reduced risk of incident sight-threatening DR. “Our findings, which are consistent with the current model of the pathogenesis of DR and data from experimental models, add to the notion of fish-derived LCω3PUFA as a healthy fat,” the authors write.
The PREDIMED study provides food for thought for those who wish to fight the complications of diabetes by clever eating, writes Michael Larsen, M.D., D.M.Sc., of Rigshospitalet-Glostrup and University of Copenhagen, Glostrup, Denmark. http://media.jamanetwork.com/news-item/greater-intake-of-dietary-omega-3-fatty-acids-associated-with-lower-risk-of-diabetic-retinopathy-among-individuals-with-type-2-diabetes/
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