diabetic retinopathy tagged posts

Treatment with norrin helps maintain healthy blood vessels and preserve vision in diabetic rats

Millions of people in the U.S. are affected by diabetic retinopathy, a complication of diabetes that affects the eyes. The condition is caused by damage to the blood vessels in the retina, the light-sensitive tissue at the back of the eye. At first, diabetic retinopathy might not cause any symptoms, or the problems might be mild. However, if the underlying diabetes remains poorly managed, it can lead to blindness.

In a new study, University of Michigan researchers showed that treatment with the molecule norrin can prevent vision loss in diabetic rats. The study is published in the journal Diabetes.

Diabetic retinopathy treatment
Current therapies for diabetic retinopathy target vascular endothelial growth factor, or VEGF, a protein that causes new blood vessels to form.

VEGF a...

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Powerful Enzyme that Tamps Down Inflammation Holds Promise for Protecting the Eyes in Diabetes, Premature Birth

Drs. Ruth and William Caldwell

An enzyme under study to treat certain cancers is also showing promise in reducing the significant vision damage that can result from diabetes and premature birth, scientists report.

Inflammation is considered a hallmark of cancer. It’s pervasive as well in both of these potentially blinding eye conditions, in which inadequate oxygen to the eyes prompts growth of new blood vessels to better deliver oxygen, but which instead often obstruct the vision pathway and become leaky, which causes swelling, further hindering vision.

Scientists at the Medical College of Georgia report in newly published studies in the journals Cell Death and Disease and Cells, increasing evidence that making more of the enzyme arginase 1, or A1, available helps alleviate these...

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Smart LED Contact Lenses for Treating Diabetic Retinopathy

Diabetes is a long-term chronic disease with many complications and requires care over a lifetime. The longer a patient suffers from diabetes, the higher the risk of developing retinopathy which can progressively lead to a decline in vision and even to blindness.

A POSTECH research team led by Professor Sei Kwang Hahn and Ph.D. candidate Geon-Hui Lee (Department of Materials Science and Engineering) in collaboration with Dr. Sangbaie Shin of PHI BIOMED Co. has recently developed a smart contact lens-type wearable device to prevent diabetic retinopathy and treat it in its early stages by irradiating 120 µW far red/LED light to the retina. This technology for smart LED contact lens has attracted a great attention for various ophthalmologic diseases.

Diabetic retinopathy is curren...

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Greater intake of dietary Omega-3 fatty acids associated with lower risk of Diabetic Retinopathy

Eating oily fish twice a week can protect your eyesight a study has revealed

Eating oily fish twice a week can protect your eyesight a study has revealed

In middle-aged and older individuals with type 2 diabetes, intake of at least 500 mg/d of dietary long-chain ω-3 polyunsaturated fatty acids, easily achievable with 2 weekly servings of oily fish, was associated with a decreased risk of sight-threatening diabetic retinopathy, according to a study published online by JAMA Ophthalmology.

Given the economic and societal burden of DR, developing effective strategies to prevent or at least delay its onset is a major public health issue. The retina is rich in long-chain ω-3 polyunsaturated fatty acids (LCω3PUFAs). Experimental models support dietary LCω3PUFA protection against DR, but clinical data are lacking. Aleix Sala-Vila, D.Pharm., Ph.D...

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