New devices: “Stent Retrievers”, which reverse Ischemic strokes, are revolutionizing treatment

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Solitaire is one of two approved stent retrievers used to treat some strokes.

Solitaire is one of two approved stent retrievers used to treat some strokes.

“Stent retrievers are a major advance in acute ischemic stroke care and will have significant impact on the evolution of stroke systems of care,” according to Loyola Medicine neurologists Rick Gill, MD and Prof. Michael J. Schneck, MD.

87% of strokes are ischemic, ie caused by clots that block blood flow to a portion of the brain. In selected patients, stent retrievers can be used to remove such clots. Loyola used stent retrievers on 34 patients in 2015, and 21 patients during the first six months of 2016.

A stent retriever is a self-expanding mesh tube attached to a wire, which is guided through a catheter. The endovascular specialist inserts the catheter in an artery in the groin and guides the catheter through various blood vessels all the way up to the brain. Once the stent retriever reaches the blockage, the endovascular specialist deploys it. The device pushes the gelatinous blood clot against the wall of the blood vessel, immediately restoring blood flow. The stent retriever then is used to grab the clot, which is pulled out when the surgeon removes the catheter.Solitaire is one of two approved stent retrievers used to treat some strokes.

Drs. Gill and Schneck describe how the current generation of stent retrievers, including the TREVO and Solitaire devices, are a remarkable improvement over earlier devices such as MERCI and Penumbra that employed different technology. Studies of these earlier devices showed results that were equivocal at best. But more recent trials of stent retrievers consistently show the newer devices are clearly superior to the intravenous drug tissue plasminogen activator (tPA) alone in reducing disability from strokes.

The clot-busting drug tPA can restore blood flow and limit stroke damage, if it is given within 4.5 hours of the onset of the stroke and the clot is small enough. (If the patient is older than 80, the cutoff time is 3 hours.) But in many patients, tPA either would not be safe to take, or would not be sufficient by itself to restore blood flow. In such patients, stent retrievers often can be used to remove the clot.

Stent retrievers also will affect where stroke patients are treated. Paramedics will play an important role in routing higher severity stroke patients, who could benefit from stent retrievers, to centers that have the capability to perform neuroendovascular procedures, Drs. Gill and Schneck write.

http://www.eurekalert.org/pub_releases/2016-06/luhs-ndc062416.php

http://news.heart.org/stent-retrievers-revolutionize-treatment-for-severe-strokes/