tPA tagged posts

COVID-19: Stopgap Measure to Treat Respiratory Distress

Researchers from MIT and the University of Colorado at Denver propose using a protein called tissue plasminogen activator, whose structure is shown here, to treat Covid-19 patients in acute respiratory distress.
Image: Wikimedia, MedicineFTWq; edited by MIT News

Researchers at MIT and the University of Colorado at Denver have proposed a stopgap measure that they believe could help Covid-19 patients who are in acute respiratory distress. By repurposing a drug that is now used to treat blood clots, they believe they could help people in cases where a ventilator is not helping, or if a ventilator is not available.

Three hospitals in Massachusetts and Colorado are developing plans to test this approach in severely ill Covid-19 patients...

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New devices: “Stent Retrievers”, which reverse Ischemic strokes, are revolutionizing treatment

Solitaire is one of two approved stent retrievers used to treat some strokes.

Solitaire is one of two approved stent retrievers used to treat some strokes.

“Stent retrievers are a major advance in acute ischemic stroke care and will have significant impact on the evolution of stroke systems of care,” according to Loyola Medicine neurologists Rick Gill, MD and Prof. Michael J. Schneck, MD.

87% of strokes are ischemic, ie caused by clots that block blood flow to a portion of the brain. In selected patients, stent retrievers can be used to remove such clots. Loyola used stent retrievers on 34 patients in 2015, and 21 patients during the first six months of 2016.

A stent retriever is a self-expanding mesh tube attached to a wire, which is guided through a catheter...

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