Immune cells get transformed into fungus-fighting nanoparticles

Black circular blobs on a gray background.
Transmission electron microscopy image of the antifungal nanodiscs. Image courtesy of Liangfang Zhang lab

Tiny particles made from the membranes of human immune cells could offer a promising new way to fight fungal infections that are becoming harder to treat. Engineers at the University of California San Diego created antifungal nanoparticles that target Candida albicans, a fungus responsible for oral and vaginal yeast infections as well as life-threatening bloodstream infections. In mice with severe Candida infections, the nanoparticles greatly reduced the amount of fungus in major organs and significantly improved survival.

The research, published in Cell Biomaterials, was led by Liangfang Zhang, a professor in the Aiiso Yufeng Li Family Department of Chemical and Nano Engineerin...

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Daydreaming algorithm helps AI remember what matters

ai thinking
Credit: Pixabay/CC0 Public Domain

During the day, our brain acquires new memories; at night, during sleep, it consolidates the important ones and eliminates the useless ones. A similar principle has been applied to Hopfield networks, one of the classic models of artificial intelligence inspired by the workings of the brain. In 2025, Federico Ricci-Tersenghi and colleagues developed Daydreaming, an algorithm that combines the learning of new memories with the elimination of spurious ones, drastically improving the network’s capacity.

One limitation remained, however. These networks lose effectiveness when they work with real-world data, which are rarely perfectly balanced—for example, very bright or very dark images, in which white or black pixels overwhelmingly dominate...

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Magnetic fingerprint of a cosmic explosion detected for the first time

This illustration depicts Faraday rotation in the afterglow of a gamma-ray burst. A powerful jet (upper left) sends polarized radio waves outward through the thin wall of a surrounding bubble of magnetized gas called an HII region. As the light passes through this material, its polarization angle is twisted by the magnetic field. Because the effect is stronger at longer wavelengths, the red and blue waves, which represent different radio wavelengths, exit the bubble oscillating in different directions. By measuring this difference, astronomers were able to map the magnetic environment surrounding GRB 260310A for the first time.
Credit: NSF/AUI/NSF NRAO/M.Weiss

Astronomers have made a series of landmark observations of one of the universe’s most violent events. Using the U.S...

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Physicists say quantum mechanics may not need imaginary numbers after all

Physicists from Heinrich Heine University Düsseldorf (HHU) have examined a fundamental property of quantum mechanics in collaboration with the German Aerospace Center (DLR). In the scientific journal Physical Review Letters, they show that this theory does not necessarily need to be formulated with imaginary numbers – real numbers can in fact also be used.

Quantum mechanics is the branch of physics that explains how matter and energy behave at the atomic and subatomic scale. Developed in the early 1900s by pioneers including Max Planck, Niels Bohr, Werner Heisenberg, and Erwin Schrödinger, it has become one of the most successful scientific theories ever created.

The theory accurately describes a wide range of microscopic phenomena...

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