Parkinson’s, Cancer, type 2 Diabetes Share a Key Element that Drives Disease

Enzyme with central role in cancer and type 2 diabetes also activates. Researchers have discovered a direct link between a master sensor of cell stress and a protein that protects the power stations of cells. The same pathway is also tied to type 2 diabetes and cancer, which could open a new avenue for treating all three diseases.

When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell’s most important players. During the rush, a protein called Parkin hurries to protect the mitochondria, the power stations that generate energy for the cell. Now Salk researchers have discovered a direct link between a master sensor of cell stress and Parkin itself...

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A Breakthrough that Enables Practical Semiconductor Spintronics

Illustration of the nanostructure.
In the opto-spintronic nanostructure, an electron spin polarisation degree greater than 90% is achieved at room temperature in a quantum dot, via remote defect-enabled spin filtering through an adjacent layer of gallium nitrogen arsenide (GaNAs). When such a spin polarised electron recombines, it emits chiral light. The spin state of the electron determines whether the electromagnetic field of the light will rotate clockwise or anticlockwise around the direction of travel. Yuqing Huang

It may be possible in the future to use information technology where electron spin is used to store, process and transfer information in quantum computers. It has long been the goal of scientists to be able to use spin-based quantum information technology at room temperature...

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First Transiting Exoplanet’s ‘Chemical Fingerprint’ reveals its Distant Birthplace

Exoplanet HD 209458b transits its star. The illuminated crescent and its colours have been exaggerated to illustrate the light spectra that the astronomers used to identify the six molecules in its atmosphere.

Astronomers have found evidence that the first exoplanet that was identified transiting its star could have migrated to a close orbit with its star from its original birthplace further away.

Analysis of the planet’s atmosphere by a team including University of Warwick scientists has identified the chemical fingerprint of a planet that formed much further away from its sun than it currently resides...

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A Drug that can Stop Tumors from Growing

Scientists detail new work on NLRP3, an intracellular complex that has been found to participate in melanoma-mediated inflammation, leading to tumor growth and progression. By inhibiting NLRP3, the researchers found, they can reduce inflammation and the resultant tumor expansion.

Cancer doctors may soon have a new tool for treating melanoma and other types of cancer, thanks to work being done by researchers at the University of Colorado Cancer Center.

Specifically, NLRP3 promotes inflammation by inducing the maturation and release of interleukin-1-beta, a cytokine that causes inflammation as part of the normal immune response to infection. In cancer, however, inflammation can cause tumors to grow and spread.

“NLRP3 is a member of a larger family that is involved in sensing da...

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