Data-driven discovery of Biomarkers pave way for improved Diagnosis of Contact Allergy

IHC staining of chemical exposed human skin. 

With the help of algorithms, researchers at Karolinska Institutet in Sweden have identified markers that can differentiate between irritant eczema and contact allergy, two skin reactions that look similar but require different treatment. Their findings, which are published in the journal Proceedings of the National Academy of Sciences (PNAS), support the further development of an alternative to today’s diagnostic patch tests.

About 20 percent of the population of high-income countries are troubled by contact eczema, a disease often associated with exposure to chemicals in the working environment...

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The Farthest Galaxy in the universe

A starfield
Far far away. Due to the expansion of the universe, even though the galaxy GN-z11 is 13.4 billion years old, the light from it has travelled 32 billion light years to reach us. Image: Pixabay CC-0

Chemical Signatures give away the distance to the most distant galaxy

A team of astronomers used the Keck I telescope to measure the distance to an ancient galaxy. They deduced the target galaxy GN-z11 is not only the oldest galaxy but also the most distant. It’s so distant it defines the very boundary of the observable universe itself. The team hopes this study can shed light on a period of cosmological history when the universe was only a few hundred million years old.

We’ve all asked ourselves the big questions at times: “How big is the universe?” or “How and when did galaxies form?”...

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Compound derived from Thunder god vine could help Pancreatic Cancer patients

Thunder God Vine

The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest how a compound derived from the thunder god vine — an herb used in China for centuries to treat joint pain, swelling and fever — is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer.

The medicinal plant’s key ingredient, triptolide, is the basis of a water-soluble prodrug called Minnelide, which appears to attack pancreatic cancer cells and the cocoon of stroma surrounding the tumor that shields it from the body’s immune system. Investigators recently published the study results in the journal Oncogenesis.

The study found that the compound’s mechanism of action is the ability of...

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Japan space agency finds ample Soil, Gas from Asteroid

This Dec. 14, 2020, photo released by the Japan Aerospace Exploration Agency (JAXA), shows black grains, right, thought to be from Ryugu are inside the sample container of the re-entry capsule of Hayabusa2, in Sagamihara, near Tokyo. Japan’s space agency said Monday it has confirmed the presence of black soil samples inside a capsule that the spacecraft Hayabusa2 brought back from a distant asteroid last week. (JAXA via AP)

Officials from Japan’s space agency said Tuesday they have found more than the anticipated amount of soil and gases inside a small capsule the country’s Hayabusa2 spacecraft brought back from a distant asteroid this month, a mission they praised as a milestone for planetary research.

The Japan Aerospace Exploration Agency said its staff initially spotted some bla...

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