High-Fat Diet with Antibiotic use linked to Gut Inflammation

Image of changes in sections of the cecal mucosa based on combinations of low-fat diet (LFD), high-fat diet (HFD), with streptomycin (Strep) treatment
Image of changes in sections of the cecal mucosa based on combinations of low-fat diet (LFD), high-fat diet (HFD), with streptomycin (Strep) treatment

Combining Western diet and antibiotic use is a pre- IBD risk factor. UC Davis researchers have found that combining a Western-style high-fat diet with antibiotic use significantly increases the risk of developing pre-inflammatory bowel disease (pre-IBD). The study, published July 14 in Cell Host and Microbe, suggests that this combination shutsdown the mitochondria in cells of the colon lining, leading to gut inflammation.

Irritable bowel syndrome (IBS) affects approximately 11% of people worldwide. It is characterized by recurring episodes of abdominal pain, bloating and changes in bowel habits...

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Tech to help Autonomous Vehicles better Scan for nearby Fast-Moving Objects

New technology uses acoustics to better control a pulse of laser light split into a frequency comb, potentially helping lidar to achieve detection of nearby high-speed objects. (WoogieWorks graphic/Alex Mehler)

Mechanical control and modulation of light on a silicon chip could enhance lidar. Researchers have built a way that lidar could achieve higher-resolution detection of nearby fast-moving objects through mechanical control and modulation of light on a silicon chip.

A self-driving car has a hard time recognizing the difference between a toddler and a brown bag that suddenly appears into view because of limitations in how it senses objects using lidar.

The autonomous vehicle industry is exploring “frequency modulated continuous wave” (FMCW) lidar to solve this problem...

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Breakthrough in Deciphering Birth of Supermassive Black Holes

Black hole image
A research team led by Cardiff University scientists say they are closer to understanding how a supermassive black hole (SMBH) is born thanks to a new technique that has enabled them to zoom in on one of these enigmatic cosmic objects in unprecedented detail.

Astronomers zoom in on black hole with one of the lowest masses ever observed in nearby. A research team led by Cardiff University scientists say they are closer to understanding how a supermassive black hole (SMBH) is born thanks to a new technique that has enabled them to zoom in on one of these enigmatic cosmic objects in unprecedented detail.

Scientists are unsure as to whether SMBHs were formed in the extreme conditions shortly after the big bang, in a process dubbed a ‘direct collapse’, or were grown much later from ‘seed...

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Scientists discover Key Element of Strong Antibody response to COVID-19

Many anti-SARS-CoV-2 antibodies are produced by a common antibody gene. X-ray crystallography revealed how specific features of these antibodies (two of which are depicted here in yellow and orange, attached to the virus) enable potent recognition of the virus’s spike protein. Graphic by Meng Yuan, Hejun Liu and Nicholas Wu in the Wilson lab.

The findings support many vaccine strategies being used to tackle the new coronavirus. A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.

The scientists, whose study appears July 13 in Science, reviewed data on nearly 300 anti-SARS-CoV-2 antibodies that their labs and others have found in convalescent COVID...

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