Hippocampus MRI
Confocal image of a mouse brain tissue shows the astrocytes (red) and neurons (green). (UCR/Ethell lab)

A team led by a biomedical scientist at the University of California, Riverside has found a new mechanism responsible for the abnormal development of neuronal connections in the mouse brain that leads to seizures and abnormal social behaviors.

The researchers focused on the hippocampus, which plays an important role in learning and social interactions; and synapses, specialized contacts between neurons.

Each neuron in the brain receives numerous excitatory and inhibitory synaptic inputs...

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Engineers Create Micron-Scale Optical Tweezers

Nanotweezer (Justus Ndukaife)

In 2018, one-half of the Nobel Prize was awarded to Arthur Ashkin, the physicist who developed optical tweezers, the use of a tightly focused laser beam to isolate and move micron-scale objects (the size of red blood cells). Now Justus Ndukaife, assistant professor of electrical engineering at Vanderbilt University, has developed the first-ever opto-thermo-electrohydrodynamic tweezers, optical nanotweezers that can trap and manipulate objects on an even smaller scale.

The article, “Stand-off trapping and manipulation of sub-10 nm objects and biomolecules using opto-thermo-electrohydrodynamic tweezers” was published online in the journal Nature Nanotechnology on August 31.

The article was authored by Ndukaife and graduate students Chuchuan Hong and Se...

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Europe’s largest Solar Telescope GREGOR unveils Magnetic Details of the Sun

Europe’s largest solar telescope GREGOR reveals intricate structures of solar magnetic fields in very high resolution. The image was taken at the wavelength of 516 nm. Credit: KIS

By studying the magnetism on the Sun, we can understand its influence on Earth and minimize damage of satellites and technological infrastructure. The GREGOR telescope allows scientists to resolve details as small as 50 km on the Sun, which is a tiny fraction of the solar diameter of 1.4 million km. This is as if one saw a needle on a soccer field perfectly sharp from a distance of one kilometer.

“This was a very exciting, but also extremely challenging project. In only one year we completely redesigned the optics, mechanics, and electronics to achieve the best possible image quality.” said Dr...

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Elderly People protected against Respiratory Infections by BCG Vaccine

ACTIVATE: Randomized Clinical Trial of BCG Vaccination Against Infection in the Elderly. Cell, Aug. 31, 2020; DOI: 10.1016/j.cell.2020.08.051

However, the effect of the vaccine specifically against COVID-19 has not been demonstrated. The BCG vaccine, an old treatment originally developed for tuberculosis, has a broad, stimulating effect on the immune system. This gives it an effective preventive action against various infections — possibly also against COVID-19. It is frequently given to children, but in this double-blind randomized clinical study, a collaboration between Radboud University Medical Center and the National and Kapodistrian University of Athens it was shown that elderly people also benefit from it. The results of the study are in Cell.

At Radboudumc, Professor of Expe...

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