A drug candidate developed by Salk researchers, and previously shown to slow aging in brain cells, successfully reversed memory loss in a mouse model of inherited Alzheimer’s disease. The new research, published online in July 2020 in the journal Redox Biology, also revealed that the drug, CMS121, works by changing how brain cells metabolize fatty molecules known as lipids.

“This was a more rigorous test of how well this compound would work in a therapeutic setting than our previous studies on it,” says Pamela Maher, a senior staff scientist in the lab of Salk Professor David Schubert and the senior author of the new paper...

Purdue University innovators are working on inventions to use micro-chip technology in implantable devices and other wearable products such as smart watches to improve biomedical devices, including those used to monitor people with glaucoma and heart disease.

The Purdue team developed a fully implantable radio-frequency transmitter chip for wireless sensor nodes and biomedical devices. The research is published in the journal IEEE Transactions on Circuits and Systems II. The transmitter chip consumes lowest amount of energy per digital bit published to date.

The transmitter works in a similar fashion to communication technology in mobile phone...

Small telescope and inexpensive diffuser key to results. New detailed observations with NSF’s NOIRLab facilities reveal a young exoplanet, orbiting a young star in the Hyades cluster, that is unusually dense for its size and age. Weighing in at 25 Earth-masses, and slightly smaller than Neptune, this exoplanet’s existence is at odds with the predictions of leading planet formation theories.

New observations...

The University of Kent’s School of Biosciences and the Institute of Medical Virology at Goethe-University, Frankfurt am Main, have identified that a glycoprotein known as transferrin may critically contribute to severe forms of COVID-19.

SARS-CoV-2 is the coronavirus that causes COVID-19. It is currently not known why some individuals develop only mild or no symptoms when infected, whilst others experience severe, life-threatening forms of the disease. However, it is known that the risk of COVID-19 becoming severe increases with age and is higher in males than in females. Many severe COVID-19 cases are characterised by increased blood clotting and thrombosis formation.

The team combined existing data on gene expres...