New Blood Test shows great promise in the diagnosis of Alzheimer’s disease

Plasma P-tau217 Concentrations in the Neuropathology Cohort

A new blood test demonstrated remarkable promise in discriminating between persons with and without Alzheimer’s disease and in persons at known genetic risk may be able to detect the disease as early as 20 years before the onset of cognitive impairment, according to a large international study published today in the Journal of the American Medical Association (JAMA) and simultaneously presented at the Alzheimer’s Association International Conference.

For many years, the diagnosis of Alzheimer’s has been based on the characterization of amyloid plaques and tau tangles in the brain, typically after a person dies...

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New Fabric could help keep you Cool in the Summer, even Without A/C

Abstract Image
Thermoconductive, Moisture-Permeable, and Superhydrophobic Nanofibrous Membranes with Interpenetrated Boron Nitride Network for Personal Cooling Fabrics

Air conditioning and other space cooling methods account for about 10% of all electricity consumption in the U.S., according to the U.S. Energy Information Administration. Now, researchers reporting in ACS Applied Materials & Interfaces have developed a material that cools the wearer without using any electricity. The fabric transfers heat, allows moisture to evaporate from the skin and repels water.

Cooling off a person’s body is much more efficient than cooling an entire room or building...

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How Stony-Iron Meteorites form

View into the SAPHiR multi-anvil press at the FRM II.
View into the SAPHiR multi-anvil press at the FRM II.Image: W. Schürmann / TUM

SAPHiR multi-anvil press solves mystery of the solar system. Meteorites give us insight into the early development of the solar system. Using the SAPHiR instrument at the Research Neutron Source Heinz Maier-Leibnitz (FRM II) at the Technical University of Munich (TUM), a scientific team has for the first time simulated the formation of a class of stony-iron meteorites, so-called pallasites, on a purely experimental basis.

“Pallasites are the optically most beautiful and unusual meteorites,” says Dr. Nicolas Walte, the first author of the study, in an enthusiastic voice. They belong to the group of stony-iron meteorites and comprise green olivine crystals embedded in nickel and iron...

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A new way to Target Cancers using ‘Synthetic Lethality’

Three dimensional culture of human breast cancer cells.
Photo credit: NCI Center for Cancer Research.

Approach exploits tumor weaknesses when 2 genetic defects are combined. Researchers report that inhibiting a key enzyme caused human cancer cells associated with two major types of breast and ovarian cancer to die and in mouse studies reduced tumor growth.

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of “synthetic lethality,” exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells.

Synthetic lethality results when non-lethal mutations in different genes become deadly when combined in cells.

The research team, led by senior study author Richard D...

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