Scientists from the Antibody and Vaccine group at the University of Southampton have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular “switch.”

This work, published in the journal Cancer Cell, focuses on a molecule called CD40 which is present on the surface of immune cells and controls both autoimmunity and cancer. In autoimmunity, CD40 is thought to be over-stimulated, increasing the chance of the immune system attacking healthy tissues; whereas in cancer, CD40 is believed to be under-stimulated, enabling tumour cells to evade the immune system. Targeting of CD40 with antibody drugs is ongoing in therapeutic interventions for both diseases.

Accordingly, antibody...

Researchers have created a device called a ‘shadow-effect energy generator’ that makes use of the contrast in illumination between lit and shadowed areas to generate electricity. This novel concept opens up new approaches in harnessing indoor lighting conditions to power electronics.

Shadows are often associated with darkness and uncertainty. Now, researchers from the National University of Singapore (NUS) are giving shadows a positive spin by demonstrating a way to harness this common but often overlooked optical effect to generate electricity.

“Shadows are omnipresent, and we often...

An extraordinary asteroid with comet-like features has researchers puzzled. We often think of asteroids and comets as distinct types of small bodies, but astronomers have discovered an increasing number of “crossovers.” These objects initially appear to be asteroids, and later develop activity, such as tails, that are typical of comets.

Now, the University of Hawai’i Asteroid Terrestrial-impact Last Alert System (ATLAS) has discovered the first known Jupiter Trojan asteroid to have sprouted a comet-like tail. ATLAS is a NASA-funded project using wide-field telescopes to rapidly scan the sky for asteroids that might pose an impact threat to Earth...

Researchers from Monash, Swinburne and RMIT universities have successfully tested and recorded Australia’s fastest internet data speed, and that of the world, from a single optical chip—capable of downloading 1000 high definition movies in a split second.

Published in the prestigious journal Nature Communications, these findings have the potential to not only fast-track the next 25 years of Australia’s telecommunications capacity, but also the possibility for this home-grown technology to be rolled out across the world.

In light of the pressures being placed on the world’s internet infrastructure, recently highlighted by isolation policies as a result of COVID-19, the research team led by Dr...