Intermittent Fasting: live ‘fast,’ live longer?

12-26-19  Intermittent Fasting: Live ‘Fast,’ Live longer? (infographic).png.png

Does scientific evidence support the claims made for these diets? In a review article published in the Dec. 26 issue of The New England Journal of Medicine, Johns Hopkins Medicine neuroscientist Mark Mattson, Ph.D., concludes that intermittent fasting does.

Mattson, who has studied the health impact of intermittent fasting for 25 years, and adopted it himself about 20 years ago, writes that “intermittent fasting could be part of a healthy lifestyle.” A professor of neuroscience at the Johns Hopkins University School of Medicine, Mattson says his new article is intended to help clarify the science and clinical applications of intermittent fasting in ways that may help physicians guide patients who want to try it.

Intermittent fasting diets, he says, fall generally into two catego...

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New Polymer material may help Batteries become Self-Healing, Recyclable

Materials science and engineering professor Christopher Evans, right, and graduate student Brian Jing have developed a solid battery electrolyte that is both self-healing and recyclable. Credit: L. Brian Stauffer

Lithium-ion batteries are notorious for developing internal electrical shorts that can ignite a battery’s liquid electrolytes, leading to explosions and fires. Engineers at the University of Illinois have developed a solid polymer-based electrolyte that can self-heal after damage – and the material can also be recycled without the use of harsh chemicals or high temperatures.

The new study, which could help manufacturers produce recyclable, self-healing commercial batteries, is published in the Journal of the American Chemical Society.

As lithium-ion batteries go throug...

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Astronomers describe a Violent Black Hole Outburst that provides new insight into Galaxy Cluster Evolution

Giant cavities in the X-ray emitting intracluster medium (shown in blue, as observed by NASA’s Chandra X-ray Observatory) have been carved out by a black hole outburst. X-ray data are overlaid on top of optical data from the Hubble Space Telescope (in red/orange), where the central galaxy that is likely hosting the culprit supermassive black hole is also visible. Credit: Massachusetts Institute of Technology

Billions of years ago, in the center of a galaxy cluster far, far away (15 billion light-years, to be exact), a black hole spewed out jets of plasma. As the plasma rushed out of the black hole, it pushed away material, creating two large cavities 180 degrees from each other...

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For CRISPR, Tweaking DNA fragments before Inserting yields Highest Efficiency Rates yet

Image result for Gene KI strategy using Cas9 RNP and end-modified dsDNA donors.
Gene KI strategy using Cas9 RNP and end-modified dsDNA donors.

University of Illinois researchers achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9 gene-editing system, a necessary step for harnessing CRISPR for clinical gene-therapy applications.

By chemically tweaking the ends of the DNA to be inserted, the new technique is up to five times more efficient than current approaches. The researchers saw improvements at various genetic locations tested in a human kidney cell line, even seeing 65% insertion at one site where the previous high had been 15%.

Led by chemical and biomolecular engineering professor Huimin Zhao, the researchers published their work in the journal Nature Chemical Biology...

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