Scorpion Toxin that Targets ‘Wasabi Receptor’ may help Solve Mystery of Chronic Pain

A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and PainCell, 2019; DOI: 10.1016/j.cell.2019.07.014

Researchers at UC San Francisco and the University of Queensland have discovered a scorpion toxin that targets the “wasabi receptor,” a chemical-sensing protein found in nerve cells that’s responsible for the sinus-jolting sting of wasabi and the flood of tears associated with chopping onions. Because the toxin triggers a pain response through a previously unknown mechanism, scientists think it can be used as a tool for studying chronic pain and inflammation, and may eventually lead to the development of new kinds of non-opioid pain relievers.

The scientists isolated the toxin, a short protein (or peptide) that they dubbed the “wasabi receptor toxin” (W...

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Storms on Jupiter are disturbing the Planet’s Colorful Belts

ALMA’s view of Jupiter at radio wavelengths (top) and the Hubble Space Telescope’s view in visible light (bottom). The eruption in the South Equatorial Belt is visible in both images: a dark spot in radio, a bright spot in visible. (ALMA image by Imke de Pater and S. Dagnello; Hubble image courtesy of NASA)

Radio, IR and optical observations show evolution of plumes and their impact on belts and zones. Storm clouds rooted deep in Jupiter’s atmosphere are affecting the planet’s white zones and colorful belts, creating disturbances in their flow and even changing their color.

Thanks to coordinated observations of the planet in January 2017 by six ground-based optical and radio telescopes and NASA’s Hubble Space Telescope, a University of California, Berkeley, astronomer and her ...

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Australian Men’s Life Expectancy Tops Other Men’s

Michel Guillot, Collin F. Payne. Tracking progress in mean longevity: The Lagged Cohort Life Expectancy (LCLE) approachPopulation Studies, 2019; DOI: 10.1080/00324728.2019.1618480

Australian men are now living longer than any other group of males in the world, according to new research from The Australian National University (ANU). The study introduces a new way of measuring life expectancy, accounting for the historical mortality conditions that today’s older generations lived through. By this measure, Australian men, on average, live to 74.1.

The news is good for Australian women too; the study shows they’re ranked second, behind their Swiss counterparts.

Dr Collin Payne co-led the study, which used data from 15 countries across Europe, North America and Asia with high life...

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Lasers enable Engineers to Weld Ceramics, no furnace required

Laser welded ceramic assembly consisting of a transparent cylindrical cap joined to a ceramic tube. Photo courtesy of Garay lab

Smartphones that don’t scratch or shatter. Metal-free pacemakers. Electronics for space and other harsh environments. These could all be made possible thanks to a new ceramic welding technology developed by a team of engineers at the University of California San Diego and the University of California Riverside.

The process, published in the Aug. 23 issue of Science, uses an ultrafast pulsed laser to melt ceramic materials along the interface and fuse them together. It works in ambient conditions and uses less than 50 watts of laser power, making it more practical than current ceramic welding methods that require heating the parts in a furnace.

Ceramics...

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