Tumor cells circulating in blood are markers for the early detection and prognosis of cancer. However, detection of these cells is challenging because of their scarcity. In the journal Angewandte Chemie, scientists have now introduced an ultrasensitive method for the direct detection of circulating tumor cells in blood samples. It is based on the amplified, time-resolved fluorescence measurement of luminescent lanthanide ions released from nanoparticles that bind specifically to tumor cells.

Conventional techniques for the detection of circulating tumor cells require complicated enrichment before detection because a sample of 10 million blood cells only contains about one tumor cell...

An international team of astrophysicists from Southampton, Oxford and South Africa have detected a very hot, dense outflowing wind close to a black hole at least 25,000 light-years from Earth.

Lead researcher Professor Phil Charles from the University of Southampton explained that the gas (ionised helium and hydrogen) was emitted in bursts which repeated every 8 minutes, the first time this behaviour has been seen around a black hole. The findings have been published in the journal Monthly Notices of the Royal Astronomical Society.

The object Professor Charles’ team studied was Swift J1357...

Scientists at the German Center for Neurodegenerative Diseases (DZNE) have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal Neuron.

It is commonly accepted that neurons of the central nervous system shut down their ability to grow when they no longer need it; this occurs normally after they have found their target cells and established synapses. However, recent findings show that old nerve cells have the potential to regrow and to repair damage similar to young neurons...

A recipe for creating a microscopic crystal structure that can hold 2 wavelengths of light at once is a step toward faster telecommunications and quantum computers. Five years ago, Stanford postdoctoral scholar Momchil Minkov encountered a puzzle that he was impatient to solve. At the heart of his field of nonlinear optics are devices that change light from one color to another – a process important for many technologies within telecommunications, computing and laser-based equipment and science...