Alzheimer’s disease Protein links Plaques to Cell Death in mice

MRI scans of CAPON-overexpressing mouse brains scanned 7 days and 3 months after CAPON cDNA introduction to AD mice.
CREDIT: RIKEN

A new protein involved in Alzheimer’s disease (AD) has been identified by researchers at the RIKEN Center for Brain Science (CBS). CAPON may facilitate the connection between the two most well-known AD culprits, amyloid plaques and tau pathology, whose interactions cause brain cell death and symptoms of dementia. This latest finding from the Takaomi Saido group at RIKEN CBS uses a novel mouse model of AD. The study was published in Nature Communications on June 3.

Alzheimer’s disease is a complex and devastating condition characterized by plaques of amyloid-β and neurofibrillary tangles, also known as tau pathology, in the brain...

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A Polar-Bear-Inspired Material for Heat Insulation

Biomimetic Carbon Tube Aerogel Enables Super-Elasticity and Thermal Insulation

For polar bears, the insulation provided by their fat, skin, and fur is a matter of survival in the frigid Arctic. For engineers, polar bear hair is a dream template for synthetic materials that might lock in heat just as well as the natural version. Now, materials scientists in China have developed such an insulator, reproducing the structure of individual polar bear hairs while scaling toward a material composed of many hairs for real-world applications in the architecture and aerospace sectors. Their work appears June 6 in the journal Chem.

“Polar bear hair has been evolutionarily optimized to help prevent heat loss in cold and humid conditions, which makes it an excellent model for a synthetic heat ...

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Building Blocks of the Earth

Illustration of meteors streaking across Earth’s atmosphere (stock image).
Credit: © IgorZh / Adobe Stock

Research team re-calculates distribution of volatile elements. Geologists gain new insights regarding the Earth’s composition by analyzing meteorites. They conclude that the building blocks that brought volatile elements to Earth have a chemical composition similar to that of primitive carbonaceous chondrites.

The study focuses on the distribution and origin of so-called volatile elements such as zinc, lead and sulphur, which have low boiling temperatures in space...

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Irregular Sleep Patterns linked to Metabolic disorders

Woman yawning
“Biological night” is defined as the period between the onset and cessation of melatonin secretion. During this period, melatonin is secreted, blood cortisol levels rise, core body temperature goes down, and we become sleepy. Melatonin is produced only during darkness and stops upon optic exposure to bright light, with light in the blue portion of the visible spectrum proving the most potent at suppressing production. CREDIT: Angela Spivey, 10.1289/ehp.118-a28

Obesity, diabetes, high cholesterol more prevalent among irregular sleepers...

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