Vest helps Athletes keep their Cool

Hasegawa and Yudai Chaen (lead author of the paper) measure the heart rate, sweat rate, muscle activity and temperature of the athlete while exercising in a hot and humid environment (35°C at 50% humidity).
CREDIT
Hiroshima University

A new cooling vest for sports athletes may ensure everyone can compete safely in sweltering summer conditions such as the upcoming 2020 Summer Olympics. Strategies to cope with body heat in sports is a pressing issue. The Tokyo Olympics will be held in the hot and muggy Japanese summer where the ambient temperature is expected to be above 33°C. Athletes have to worry about performing under pressure of the high-stakes competition but also now have to deal with a very hot and humid climate...

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Key Protein: Lab solves HOIL-1 Mystery

A hydroxylamine-sensitive modification on HOIL-1

The mysterious function of a key protein has been revealed following a breakthrough by University of Dundee scientists. HOIL-1 is a component of the Linear Ubiquitin Assembly Complex (LUBAC) which lies at the heart of the mechanism that determines whether the cells of our body will survive or die. Now researchers working in the laboratory of Professor Sir Philip Cohen in the University’s Medical Research Council Protein Phosphorylation Unit (MRC-PPU) have found that HOIL-1 operates in tandem with a second component of LUBAC to form ubiquitin chains.

The research, which has just been published in the journal Proceedings of the National Academy of Sciences (PNAS), has also revealed that the ubiquitin chains are joined to other protein...

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NASA’s Fermi mission reveals its Highest-energy Gamma-ray bursts

Green dots show the locations of 186 gamma-ray bursts observed by the Large Area Telescope (LAT) on NASA’s Fermi satellite during its first decade. Some noteworthy bursts are highlighted and labeled. Background: Constructed from nine years of LAT data, this map shows how the gamma-ray sky appears at energies above 10 billion electron volts. The plane of our Milky Way galaxy runs along the middle of the plot. Brighter colors indicate brighter gamma-ray sources.
Credit: NASA/DOE/Fermi LAT Collaboration

For 10 years, NASA’s Fermi Gamma-ray Space Telescope has scanned the sky for gamma-ray bursts (GRBs), the universe’s most luminous explosions. A new catalog of the highest-energy blasts provides scientists with fresh insights into how they work.

“Each burst is in some way unique,” said...

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Topical Cream shows promise in Treatment of Skin Pigmentation disease, Vitiligo

Hands with vitiligo
“Topical ruxolitinib has the potential to change the way vitiligo is treated. Not only is it effective at repigmenting the skin, but it has an excellent safety profile,” said Dr. Rosmarin.

A nationwide phase II clinical trial, coordinated out of Tufts Medical Center in Boston, has found that a topical cream was extremely effective in reversing the effects of vitiligo, a relatively common autoimmune disease that causes loss of skin pigmentation. Topical application of the medicated cream, ruxolitinib, which is currently used as an oral treatment for certain blood disorders, resulted in substantial improvement of facial vitiligo symptoms in nearly half of the trial’s participants...

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