Breakthrough toward developing Blood Test for Pain

Researchers are developing an objective test for patient pain.
Credit: © ake1150 / Fotolia

Researchers have developed a test that objectively measures pain biomarkers in blood. The test could help physicians better treat patients with precision medicine, and help stem the tide of the opioid crisis.

“We have developed a prototype for a blood test that can objectively tell doctors if the patient is in pain, and how severe that pain is. It’s very important to have an objective measure of pain, as pain is a subjective sensation. Until now we have had to rely on patients self-reporting or the clinical impression the doctor has,” said Niculescu, who worked with other Department of Psychiatry researchers on the study. “When we started this work it was a farfetched idea...

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Breakthrough in the Search for Graphene-based Electronics

Danish researchers just solved one of the biggest challenges of making effective nano electronics based on graphene: to carve out graphene to nanoscale dimensions without ruining the electrical properties. This allows them to achieve electrical currents orders of magnitude higher than previously achieved for such structures. The work shows that the quantum transport properties needed for future electronics can survive scaling down to 10 nanometer dimensions.
Credit: Otto Moesgaard

A team of researchers from Denmark has solved one of the biggest challenges in making effective nanoelectronics based on graphene. For 15 years, scientists have tried to exploit the “miracle material” graphene to produce nanoscale electronics...

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Solar Tadpole-like Jets seen with NASA’S IRIS add new clue to age-old mystery

Images from IRIS show the tadpole-shaped jets containing pseudo-shocks streaking out from the Sun (see animated GIF).
Credit: Abhishek Srivastava IIT (BHU)/Joy Ng, NASA’s Goddard Space Flight Center

Scientists have discovered tadpole-shaped jets coming out of regions with intense magnetic fields on the Sun. Unlike those living on Earth, these “tadpoles” – formally called pseudo-shocks – are made entirely of plasma, the electrically conducting material made of charged particles that account for an estimated 99% of the observable universe. The discovery adds a new clue to one of the longest-standing mysteries in astrophysics.

For 150 years scientists have been trying to figure out why the wispy upper atmosphere of the Sun – the corona is over 200 times hotter than the solar surface...

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The Key to Increased Lifespan? Rubicon Alters Autophagy in Animals during Aging


Age-dependent increase in expression of Rubicon, a negative regulator of autophagy, is a cause of age-dependent autophagic impairment and contributes to acceleration of aging in animals. Credit:
Osaka University

Autophagy is an important biological recycling mechanism that is used to maintain homeostasis (balance or equilibrium) within all types of animal tissue. Many studies have attempted to understand the relationship between the reduction of autophagy and progression of aging in animals; however, none have provided a clear explanation, until now.

In 2009, a research team led by Tamotsu Yoshimori at Osaka University identified Rubicon as a protein factor that suppresses autophagy by controlling a specific step in this pathway...

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