Tiny Implantable Device Short-Circuits Hunger Pangs, Aids Weight Loss


Graduate student Guang Yao (left) and Xudong Wang (right) hold a small implantable device that helped rats lose 40 percent of their body weights.
Credit: Sam Million-Weaver

New battery-free, easily implantable weight-loss devices developed by engineers could offer a promising new weapon for battling the bulge. In laboratory testing, the devices helped rats shed almost 40% of their body weight. Results of the study were published today (Dec. 17, 2018) in the journal Nature Communications.

Measuring less than 1cm across, or about a third of the area of a U.S...

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Fossil from the Big Bang discovered with W. M. Keck Observatory


Within the gas in the (blue) filaments connecting the (orange) galaxies lurk rare pockets of pristine gas — vestiges of the Big Bang that have somehow been orphaned from the explosive, polluting deaths of stars, seen here as circular shock waves around some orange points.
Credit: TNG COLLABORATION

Rare relic is one of only three fossil clouds known in the universe. A relic cloud of gas, orphaned after the Big Bang, has been discovered in the distant universe by astronomers using the world’s most powerful optical telescope, the W. M. Keck Observatory on Maunakea, Hawaii.

The discovery of such a rare fossil, led by PhD student Fred Robert and Professor Michael Murphy at Swinburne University of Technology, offers new information about how the first galaxies in the universe formed...

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New Epigenetic Cervical Cancer test has 100% Detection rate


A cytologic smear under the microscope

A new test for cervical cancer was found to detect all of the cancers in a randomised clinical screening trial of 15,744 women, outperforming both the current Pap smear and human papillomavirus (HPV) test at a reduced cost, according to a study led by Queen Mary University of London.

The study, published in the International Journal of Cancer, compared a new ‘epigenetics-based’ cervical cancer test with Pap smear and HPV tests, and investigated how well it predicted the development of cervical cancer up to five years in advance in a large study of women aged 25-65 in Canada.

As opposed to checking for patterns in the DNA genetic code itself that are indicative of the HPV virus, the new test looks at the naturally-occurring chemical markers that app...

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Switch-in-a-Cell Electrifies Life


Rice University scientists used E. coli bacteria as a platform to test protein switches that can be used to control the flow of electrons. Proteins placed in cells can simply be turned on and off with chemical signals.
Credit: Illustration by Josh Atkinson/Rice University

Scientists create electrical protein switches triggered by chemicals. Scientists at Rice University have developed synthetic protein switches to control the flow of electrons.

The proof-of-concept, metal-containing proteins made in the Rice lab of synthetic biologist Joff Silberg are expressed within cells upon the introduction of one chemical and are functionally activated by another chemical. If the proteins have been placed in the cell, they can simply be turned on and off...

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