Brentuximab vedotin mechanism of action.

A new combination of three drugs that harness the body’s immune system is safe and effective, destroying most cancer cells in 95% of patients with recurrent Hodgkin lymphoma, according to the results of an early-phase study.

Presented Dec. 3 at the annual meeting of the American Society of Hematology in San Diego, the study in 19 men and women found that injections of ipilimumab (marketed as Yervoy), nivolumab (Opdivo), and brentuximab vedotin (ADCETRIS) safely decreased tumor size or spread to some degree in 18 patients after at least six months of treatment, with 16 patients showing complete disappearance (remission) of tumors. After nine months of treatment, 15 remained in complete remission with no sign of their cancer’s return (relapse).

Resear...

The observatories are also releasing their first catalog of gravitational-wave events. The LIGO and Virgo collaborations have now confidently detected gravitational waves from a total of 10 stellar-mass binary black hole mergers and one merger of neutron stars, which are the dense, spherical remains of stellar explosions. Six of the black hole merger events had been reported before, while four are newly announced.

From September 12, 2015, to January 19, 2016, during the first LIGO observing run since undergoing upgrades in a program called Advanced LIGO, gravitational waves from 3 binary black hole mergers were detected...

Force Push is a novel VR technique that allows users to move objects with unprecedented nuance.
Credit: Virginia Tech

The VR interface responds to device-free nuanced hand movements. Force Push provides a more physical, nuanced experience than traditional hand controllers allow in VR. It responds to the speed and magnitude of hand gestures to accelerate or decelerate objects in a way that users can understand intuitively.

Fans of the Star Wars franchise will have to wait more than a year from now to get their fix of Jedi-laden telekinetic spectacles on the big screen. The as-of-yet-to-be-titled Episode IX, the last installment of the space saga as was envisioned in 1977, won’t be released until December 2019...

Manhattan plot of the results from the GWAS meta-analysis of ADHD.

A major international collaboration headed by researchers from the Danish iPSYCH project, the Broad Institute of Harvard and MIT, Massachusetts General Hospital, SUNY Upstate Medical University, and the Psychiatric Genomics Consortium has for the first time identified genetic variants which increase the risk of ADHD. The new findings provide a completely new insight into the biology behind ADHD.

Our genes are very important for the development of mental disorders – including ADHD, where genetic factors capture up to 75% of the risk. Until now, the search for these genes had yet to deliver clear results...