Purdue University researchers have created a drug delivery method using silicon nanoneedles with diameters 100 times smaller than a mosquito’s needle. These nanoneedles are embedded in a stretchable and translucent elastomer patch that can be worn on the skin to deliver exact doses directly into cells.
Credit: Purdue image

Minimally invasive patch delivers exact doses directly into cells, lessens pain, toxicity. Purdue University researchers have developed a new flexible and translucent base for silicon nanoneedle patches to deliver exact doses of biomolecules directly into cells and expand observational opportunities.

“This means that eight or nine silicon nanoneedles can be injected into a single cell without significantly damaging a cell...

The illustration shows a diseased kidney on the left and a healthy kidney on the right, after rectangular DNA nanostructures migrated and accumulated in the kidney, acting to alleviate damage due to oxidative stress. Graphic by Shireen Dooling.

Researchers have developed a new method for treating and preventing acute kidney injury. Their technique involves the use of tiny, self-assembling forms measuring just billionths of a meter in diameter. Each year, there are some 13.3 million new cases of acute kidney injury (AKI), a serious affliction. Formerly known as acute renal failure, the ailment produces a rapid buildup of nitrogenous wastes and decreases urine output, usually within hours or days of disease onset. Severe complications often ensue.

AKI is responsible for 1...

T-shirt with charge-storing system.
Credit: UMass Amherst/Trisha Andrew

A major factor holding back development of wearable biosensors for health monitoring is the lack of a lightweight, long-lasting power supply. Now scientists at the University of Massachusetts Amherst led by materials chemist Trisha L. Andrew report that they have developed a method for making a charge-storing system that is easily integrated into clothing for “embroidering a charge-storing pattern onto any garment.”

As Andrew explains, “Batteries or other kinds of charge storage are still the limiting components for most portable, wearable, ingestible or flexible technologies. The devices tend to be some combination of too large, too heavy and not flexible.”

Their new method uses a micro-supercapacitor and combines vapo...