New Genetic Regulators of Regeneration identified

Comparative model of lncRNA-regulation of heart regeneration. Known and novel zebrafish lncRNAs adjacent or antisense to protein-coding genes (top) were connected to a set of previously characterized genes required for heart regeneration in the zebrafish (bottom). Gene regulatory and/or protein–protein interactions from Ingenuity Pathways Analysis were used to find a minimal set of homologous genes that connect the adjacent/antisense genes to the regeneration genes.

Comparative model of lncRNA-regulation of heart regeneration. Known and novel zebrafish lncRNAs adjacent or antisense to protein-coding genes (top) were connected to a set of previously characterized genes required for heart regeneration in the zebrafish (bottom). Gene regulatory and/or protein–protein interactions from Ingenuity Pathways Analysis were used to find a minimal set of homologous genes that connect the adjacent/antisense genes to the regeneration genes.

Discovery could one day lead to new therapies to trigger regeneration in humans...

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Toward Fast-Charging Solid-State Batteries

Toward #Fast-#Charging #Solid-State #Batteries There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire.

Test set-up for the solid-state battery: the battery of the size of a button cell is located in the middle of the acrylic glass casing, which ensures permanent contact with the battery.
Credit: Forschungszentrum Jülich / Regine Panknin

There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Scientists have now introduced a new concept that allows currents up to 10X greater during charging and discharging than previously described in the literature.

The low current is considered one of the biggest hurdles in the development of solid-state batteries...

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Light from Ancient Quasars helps confirm Quantum Entanglement

This artist’s impression of one of the most distant, oldest, brightest quasars ever seen is hidden behind dust. The quasar dates back to less than one billion years after the big bang.
Credit: NASA/ESA/G.Bacon, STScI

Results are among the strongest evidence yet for ‘spooky action at a distance’. New research boosts the case for quantum entanglement. Scientists have used distant quasars, one of which emitted its light 7.8 billion years ago and the other 12.2 billion years ago, to determine the measurements to be made on pairs of entangled photons. They found correlations among more than 30,000 pairs of photons – far exceeding the limit for a classically based mechanism.

Take, for instance, two particles sitting on opposite edges of the universe...

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Nanoparticles in our Environment may have more Harmful Effects than we think

Principal outcomes of Nrf2 inactivation in HepG2 cells after a 24-h co-exposure to silver nanoparticles and cadmium (AgNP + Cd2+). Inhibition of Nrf2 prevented transcription of target genes, resulting in the downregulation of antioxidant defense proteins, pentose phosphate pathway (PPP) enzymes, and proteasome subunits (red arrows).

Principal outcomes of Nrf2 inactivation in HepG2 cells after a 24-h co-exposure to silver nanoparticles and cadmium (AgNP + Cd2+). Inhibition of Nrf2 prevented transcription of target genes, resulting in the downregulation of antioxidant defense proteins, pentose phosphate pathway (PPP) enzymes, and proteasome subunits (red arrows).

Researchers warn that a combination of nanoparticles and contaminants may form a cocktail that is harmful to our cells. In their study, 72 pct. of cells died after exposure to a cocktail of nano-silver and cadmium ions. Nanoparticles are becoming increasingly widespread in our environment. Thousands of products contain nanoparticles because of their unique properties...

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