A Photosynthetic Engine for Artificial Cells

A membrane (red outer boundary) encapsulates actin (white lines), the protein building blocks of the cytoskeleton and tissues. The actin was polymerized by coupling ATP synthesis with artificial organelles (green dots) inside the membrane. Credit: Image courtesy of the Disease Biophysics Group/Harvard University

A membrane (red outer boundary) encapsulates actin (white lines), the protein building blocks of the cytoskeleton and tissues. The actin was polymerized by coupling ATP synthesis with artificial organelles (green dots) inside the membrane. Credit: Image courtesy of the Disease Biophysics Group/Harvard University

Researchers engineered a cell-like structure that harnesses photosynthesis to perform designer reactions. In the quest to build an artificial cell, there are two approaches: The first, reengineers the genomic software of a living cell. The second, focuses on cellular hardware, building simple, cell-like structures from the ground up that mimic the function of living cells...

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Novel RNA-Modifying Tool Corrects Genetic Diseases

Professor Matthew Disney of The Scripps Research Institute led the new study. Credit: The Scripps Research Institute

Professor Matthew Disney of The Scripps Research Institute led the new study. Credit: The Scripps Research Institute

A new tool opens the possibility of creating drugs that can be taken conveniently as pills to correct genetic diseases. As scientists gain insights into which genes drive diseases, they are pursuing the next logical question: Can gene editing technologies be developed to treat or even cure those diseases? Much of that effort has focused on developing technologies such as CRISPR-Cas9, a protein-based system.

At The Scripps Research Institute campus in Florida, chemist Matthew D. Disney, PhD, has taken a different approach, developing a small-molecule-based tool that acts on RNA to selectively delete certain gene products...

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Cometh the Cyborg: Improved Integration of Living Muscles into Robots

Object manipulations performed by the biohybrid robots. Credit: Shoji Takeuchi, Institute of Industrial Science, the University of Tokyo

Object manipulations performed by the biohybrid robots. Credit: Shoji Takeuchi, Institute of Industrial Science, the University of Tokyo

Researchers have developed a novel method of growing whole muscles from hydrogel sheets impregnated with myoblasts. They then incorporated these muscles as antagonistic pairs into a biohybrid robot, which successfully performed manipulations of objects. This approach overcame earlier limitations of a short functional life of the muscles and their ability to exert only a weak force, paving the way for more advanced biohybrid robots.

The new field of biohybrid robotics involves the use of living tissue within robots, rather than just metal and plastic...

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Large Magellanic Cloud: A crowded neighborhood

Glowing brightly about 160,000 light-years away, the Tarantula Nebula is the most spectacular feature of the Large Magellanic Cloud, a satellite galaxy to our Milky Way. This image from VLT Survey Telescope at ESO's Paranal Observatory in Chile shows the region and its rich surroundings in great detail. It reveals a cosmic landscape of star clusters, glowing gas clouds and the scattered remains of supernova explosions. Credit: ESO

Glowing brightly about 160,000 light-years away, the Tarantula Nebula is the most spectacular feature of the Large Magellanic Cloud, a satellite galaxy to our Milky Way. This image from VLT Survey Telescope at ESO’s Paranal Observatory in Chile shows the region and its rich surroundings in great detail. It reveals a cosmic landscape of star clusters, glowing gas clouds and the scattered remains of supernova explosions. Credit: ESO

Glowing brightly about 160,000 light-years away, the Tarantula Nebula is the most spectacular feature of the Large Magellanic Cloud, a satellite galaxy to our Milky Way. A new image reveals a cosmic landscape of star clusters, glowing gas clouds and the scattered remains of supernova explosions. This is the sharpest image ever of this entire field.

Taking advanta...

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