It’s been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying. Now, researchers at Albert Einstein College of Medicine, part of Montefiore, have discovered the secret to the gene’s success: The enzyme it codes for generates a compound that stops viruses from replicating. The newly discovered compound, described in today’s online edition of Nature, offers a novel approach for attacking many disease-causing viruses.

“Nature has given us a template for creating a powerful and safe antiviral compound,” says study leader Steven C. Almo, Ph.D...

A newly developed stealth sheet can hide hot objects like human bodies or military vehicles from infrared cameras. Credit: PHOTO BY HONGRUI JIANG

Infrared cameras are the heat-sensing eyes that help drones find their targets even in the dead of night or through heavy fog. Hiding from such detectors could become much easier, thanks to a new cloaking material that renders objects – and people – practically invisible. “What we have shown is an ultrathin stealth ‘sheet.’ Right now, what people have is much heavier metal armor or thermal blankets,” says Hongrui Jiang, professor of electrical and computer engineering at the University of Wisconsin-Madison.

Warm objects like human bodies or tank engines emit heat as infrared light...

A snapshot of a simulated giant molecular cloud marked with with star clusters in formation. Credit: McMaster University

Clusters of stars across the vast reaches of time and space of the entire universe were all created the same way, researchers at McMaster University have determined. Researchers Corey Howard, Ralph Pudritz and William Harris used highly-sophisticated computer simulations to re-create what happens inside gigantic clouds of concentrated gases known to give rise to clusters of stars that are bound together by gravity.

The state-of-the-art simulations follow a cloud of interstellar gas 500 light years in diameter, projecting 5 million years’ worth of evolution wrought by turbulence, gravity and feedback from intense radiation pressure produced by massive stars within forming...

The fruit fly intestine shares much of the same physiology of the human intestine, just simpler and on a smaller scale. Credit: Adam Wong, PhD. Modified from Disease Models & Mechanisms. doi: 10.1242/dmm.023408.

Study teases out how ‘good bacteria’ keep us metabolically fit. The innate immune system, our first line of defense against bacterial infection, has a side job that’s equally important: fine-tuning our metabolism. The study, led by Paula Watnick, MD, PhD, of the Division of Infectious Diseases at Boston Children’s Hospital, reveals that innate immune pathways, best known as our first line of defense against bacterial infection, have a side job that’s equally important.

In the intestine, digestive cells use an innate immune pathway to respond to harmful bacteria...