Paralyzed Patient Feels Sensation again

fMRI is used to highlight select implant sites in the somatosensory cortex. Electrodes implanted in this region were able to stimulate neurons that produced physical sensations, like a squeeze or tap, in the arm of a paralyzed man. Credit: Courtesy of the Andersen lab

fMRI is used to highlight select implant sites in the somatosensory cortex. Electrodes implanted in this region were able to stimulate neurons that produced physical sensations, like a squeeze or tap, in the arm of a paralyzed man. Credit: Courtesy of the Andersen lab

For the first time, scientists at Caltech have induced natural sensations in the arm of a paralyzed man by stimulating a certain region of the brain with a tiny array of electrodes. The patient has a high-level spinal cord lesion and, besides not being able to move his limbs, also cannot feel them. The work could one day allow paralyzed people using prosthetic limbs to feel physical feedback from sensors placed on these devices.

The research was done in the laboratory of Richard Andersen, James G...

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Exotic Binary Stars

A Chandra X-ray Observatory image of the globular cluster 47 Tucanae. The image is about ten light-years across, and shows many cataclysmic variables (CVs), white dwarf stars that accrete from a companion star. Astronomers have discovered twenty-two new CVs in the cluster, and used the statistics to argue that, unlike many clusters which have bright, recently formed CVs, the ones here are older or even primordial. Credit: NASA/CXC/Michigan State/A.Steiner et al. 2014

A Chandra X-ray Observatory image of the globular cluster 47 Tucanae. The image is about ten light-years across, and shows many cataclysmic variables (CVs), white dwarf stars that accrete from a companion star. Astronomers have discovered twenty-two new CVs in the cluster, and used the statistics to argue that, unlike many clusters which have bright, recently formed CVs, the ones here are older or even primordial. Credit: NASA/CXC/Michigan State/A.Steiner et al. 2014

Cataclysmic variable stars (CVs) are white dwarf stars that are accreting from an orbiting, low mass binary companion star. The accretion is facilitated by the proximity of the stars; typical orbital periods range from about 1 to 10 hours...

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New Device Modulates Light and Amplifies Tiny Signals

This is a schematic of the first-ever plasmomechanical oscillator (PMO), developed by NIST researchers. The orange-white ovals represent the localized plasmon oscillations. The cantilever, containing the gold cuboid nanoparticle, lies dead center. The series of white curves represents the electrical field applied to the cantilever. Data at right indicates that the device can lock onto and greatly amplify weak signals that oscillate at frequencies close to those of the PMO. Credit: B. Roxworthy/NIST

This is a schematic of the first-ever plasmomechanical oscillator (PMO), developed by NIST researchers. The orange-white ovals represent the localized plasmon oscillations. The cantilever, containing the gold cuboid nanoparticle, lies dead center. The series of white curves represents the electrical field applied to the cantilever. Data at right indicates that the device can lock onto and greatly amplify weak signals that oscillate at frequencies close to those of the PMO. Credit: B. Roxworthy/NIST

Researchers have for the first time created a plasmomechanical oscillator, a nanometer-scale device that is no bigger than a red blood cell but has myriad technological applications...

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Resistance Training enhances Recycling Capacity in Muscles

A new study at the University of Jyväskylä, Finland reports that autophagosome content is increased by resistance training in previously untrained young men, but this response may be blunted by aging. Credit: University of Jyväskylä

A new study at the University of Jyväskylä, Finland reports that autophagosome content is increased by resistance training in previously untrained young men, but this response may be blunted by aging. Credit: University of Jyväskylä

A new study at the University of Jyväskylä, Finland reports that autophagosome content is increased by resistance training in previously untrained young men, but this response may be blunted by aging. Autophagy is a major catabolic route in cells responsible for the clearance of proteins and organelles. Pathological levels of autophagy are associated with muscle wasting, but physiological levels are important for cellular recycling.

In the present study, indicators of autophagy and unfolded protein response (UPR), which is another system for maintaining c...

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