A schematic image of DFB Si laser; Inset: photograph of a fabricated DFB device. (b) Emission spectra of the Si laser as a function of pump power; Background: a cross-sectional SEM image of the DFB structure.

Integrated Si photonics incorporates the essence of the two pillar industries of “microelectronics” and “optoelectronics”, which is expected to bring new technological revolution in a variety of fields such as communication, sensing, lighting, display, imaging, detection, etc. Si lasers are the key to achieve integrated Si photonics. However, the optical gains of Si are lower than those of III-V compound semiconductors by one order of magnitude or two, due to its indirect bandgap feature...

Co-author I. Altshuler sampling permafrost terrain near the McGill Arctic research station, Canadian high Arctic. Credit: Dr Jacqueline Goordial

Miniature instruments and new techniques can detect and analyze microorganisms in extreme environments resembling those on Mars. Researchers demonstrate for the first time the potential of existing technology to directly detect and characterize life on Mars and other planets. The study, published in Frontiers in Microbiology, used miniaturized scientific instruments and new microbiology techniques to identify and examine microorganisms in the Canadian high Arctic – one of the closest analogs to Mars on Earth...

Klotho proteins. Credit: Image courtesy of Yale University

Named after the Greek goddess who spun the thread of life, Klotho proteins play an important role in the regulation of longevity and metabolism. In a recent Yale-led study, researchers revealed the 3D structure of one of these proteins, beta-Klotho, illuminating its intricate mechanism and therapeutic potential. The study findings, published in Nature, could have implications for therapies developed to treat a wide range of medical conditions, including diabetes, obesity, and certain cancers, the researchers said.

The Klotho family of 2 receptor proteins are located on the surface of cells of specific tissues...

Periostin (shown in pink) is being used in the clinic as a marker for allergic diseases such as asthma as well as atopic dermatitis. Left image: Periostin is overexpressed in atopic dermatitis. Right image: Blocking LIGHT also blocks periostin expression.

Finding provides a novel therapeutic target for the treatment of severe eczema, a chronic inflammatory skin condition that is driven by an allergic reaction. In their latest study, researchers at La Jolla Institute reveal an important player that promotes skin inflammation in atopic dermatitis and the characteristic thickening of the skin...