Astronomers at UMass Amherst and in Mexico, using the Large Millimeter Telescope located on the summit of a 15,000-foot extinct volcano in Mexico’s central state of Puebla, have detected the second most distant dusty, star-forming galaxy ever found in the universe, born witin the first one billion years after the Big Bang. It is the oldest object ever detected by the LMT. Credit: UMass Amherst

Astronomy team image one of the first massive galaxies to form, 12.8 billion years ago...

Chloroquine is used to overcome the liver, a major problem in nanomedicine. Credit: Houston Methodist

A new study shows that a 70-year-old malaria drug can block immune cells in the liver so nanoparticles can arrive at their intended tumor site, overcoming a significant hurdle of targeted drug delivery, according to a team of researchers led by Houston Methodist. Many cancer patients do not respond to chemotherapies because the drugs never reach the cancer cells. Even in nanomedicine, which is one of the best new methods for delivering drugs to a tumor, only about 1% of a dose of nanoparticles will successfully arrive at the intended tumor site, while the rest are filtered out by the immune cells of the liver and spleen.

Using chloroquine, the researchers not only increased the circulation...

Diamidophosphate (DAP)

Chemists at The Scripps Research Institute (TSRI) have found a compound that may have been a crucial factor in the origins of life on Earth. Origins-of-life researchers have hypothesized that a chemical reaction called phosphorylation may have been crucial for the assembly of three key ingredients in early life forms: short strands of nucleotides to store genetic information, short chains of amino acids (peptides) to do the main work of cells, and lipids to form encapsulating structures such as cell walls. Yet, no one has ever found a phosphorylating agent that was plausibly present on early Earth and could have produced these three classes of molecules side-by-side under the same realistic conditions.

TSRI chemists have now identified just such a compound: diamidoph...

The Burton lab studies tiny, plastic particles as a model for more complex systems. The particles are suspended in a vacuum chamber filled with a plasma — ionized argon gas. Credit: Justin Burton, Emory University

Complex behavior emerges from a simple system in a fixed environment. Physicists at Emory University have shown how a system of lifeless particles can become “life-like” by collectively switching back and forth between crystalline and fluid states – even when the environment remains stable. “We’ve discovered perhaps the simplest physical system that can consistently keep changing behavior over time in a fixed environment,” says Justin Burton, Emory assistant professor of physics. “In fact, the system is so simple we never expected to see such a complex property emerge from it.”

M...