Neuroscientists Identify Source of Early Brain Activity

This image shows the selective response of a subplate neuron to sounds of different frequencies (horizontal axis) and volume levels (vertical axis). Warmer colors indicate a stronger response. Subplate neurons are among the first neurons to form in the cerebral cortex and were previously thought to serve a primarily structural role in brain development. A new study suggests that these neurons do, in fact, transmit sensory information. This cell only responded to higher frequencies, especially at low volume levels; increased volume expanded the cell's frequency range of response. Prior to this study, the ability of the cortex to selectively respond to certain sounds was thought to emerge later in brain development. Credit: Patrick Kanold

This image shows the selective response of a subplate neuron to sounds of different frequencies (horizontal axis) and volume levels (vertical axis). Warmer colors indicate a stronger response. Subplate neurons are among the first neurons to form in the cerebral cortex and were previously thought to serve a primarily structural role in brain development. A new study suggests that these neurons do, in fact, transmit sensory information. This cell only responded to higher frequencies, especially at low volume levels; increased volume expanded the cell’s frequency range of response. Prior to this study, the ability of the cortex to selectively respond to certain sounds was thought to emerge later in brain development. Credit: Patrick Kanold

Brain cells that support early structural development...

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Red Giant Star gives a surprising Glimpse of the Sun’s Future

The sky around W Hydrae, as seen in visible light. Credit: Digitized Sky Survey

The sky around W Hydrae, as seen in visible light. Credit: Digitized Sky Survey

A Chalmers-led team of astronomers has for the first time observed details on the surface of an aging star with the same mass as the Sun. The star is a giant, its diameter twice the size of Earth’s orbit around the Sun, but also that the star’s atmosphere is affected by powerful, unexpected shock waves. The research is published in Nature Astronomy on 30 October 2017. The new ALMA images show for the first time details on the surface of the red giant W Hydrae, 320 light years distant in the constellation of Hydra, the Water Snake.

W Hydrae is an example of an AGB (asymptotic giant branch) star. Such stars are cool, bright, old and lose mass via stellar winds...

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One of the Oldest Objects in the Universe Observed

Astronomers at UMass Amherst and in Mexico, using the Large Millimeter Telescope located on the summit of a 15,000-foot extinct volcano in Mexico's central state of Puebla, have detected the second most distant dusty, star-forming galaxy ever found in the universe, born witin the first one billion years after the Big Bang. It is the oldest object ever detected by the LMT. Credit: UMass Amherst

Astronomers at UMass Amherst and in Mexico, using the Large Millimeter Telescope located on the summit of a 15,000-foot extinct volcano in Mexico’s central state of Puebla, have detected the second most distant dusty, star-forming galaxy ever found in the universe, born witin the first one billion years after the Big Bang. It is the oldest object ever detected by the LMT. Credit: UMass Amherst

Astronomy team image one of the first massive galaxies to form, 12.8 billion years ago...

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Age-old Malaria Treatment found to improve Nanoparticle Delivery to Tumors

Chloroquine is used to overcome the liver, a major problem in nanomedicine. Credit: Houston Methodist

Chloroquine is used to overcome the liver, a major problem in nanomedicine. Credit: Houston Methodist

A new study shows that a 70-year-old malaria drug can block immune cells in the liver so nanoparticles can arrive at their intended tumor site, overcoming a significant hurdle of targeted drug delivery, according to a team of researchers led by Houston Methodist. Many cancer patients do not respond to chemotherapies because the drugs never reach the cancer cells. Even in nanomedicine, which is one of the best new methods for delivering drugs to a tumor, only about 1% of a dose of nanoparticles will successfully arrive at the intended tumor site, while the rest are filtered out by the immune cells of the liver and spleen.

Using chloroquine, the researchers not only increased the circulation...

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