Clinical trial shows constipation drug can treat patients with chronic kidney disease

World's first clinical trial showing lubiprostone aids kidney function
Administering lubiprostone alters gut microbiota, leading to improved mitochondrial function and suppression of inflammation. This improved renal function by increasing the levels of aguA and polyamines. Credit: Shun Watanabe

Chronic kidney disease (CKD) is a major health issue worldwide. Many patients end up requiring regular dialysis to avoid kidney failure and stay alive. Despite the severity of the condition, there are currently no drugs available that improve kidney function.

A research group led by Tohoku University Graduate School of Medicine’s Professor Takaaki Abe has found a remarkable solution to treat patients with CKD by co-opting a drug typically used for constipation...

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Optoelectronics research could bring holograms to your smartphone and closer to everyday use

New research from the University of St Andrews paves the way for holographic technology, with the potential to transform smartdevices, communication, gaming and entertainment.

In a study published in Light: Science & Applications, researchers from the School of Physics and Astronomy created a new optoelectronic device from the combined use of holographic metasurfaces (HMs) and organic light-emitting diodes (OLEDs).

Until now, holograms have been created using lasers. However, researchers have found that using OLEDs and HMs gives a simpler and more compact approach that is potentially cheaper and easier to apply, overcoming the main barriers to hologram technology being used more widely.

Organic light-emitting diodes are thin film devices widely used to make the colored pixels...

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White dwarf stars could create surprisingly common long-lived habitable zones

A comparison between the white dwarf IK Pegasi B (centre), its A-class companion IK Pegasi A (left) and the Sun (right). This white dwarf has a surface temperature of 35500 K (Credit : RJ Hall)

A new study by Manuel Barrientos and colleagues from the University of Oklahoma reveals that between 0.6% and 2.5% of white dwarfs in our solar neighborhood undergo dramatic cooling delays that could extend habitable zones for billions of additional years. The secret lies in an element known as neon-22, which, after carbon and oxygen, is the most abundant element inside white dwarfs.

When white dwarfs contain at least 2.5% neon-22 by mass, they undergo a process called “distillation” as their cores crystallize...

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The Higgs boson just revealed a new secret at the Large Hadron Collider

Scientists at CERN’s ATLAS experiment have uncovered compelling evidence of Higgs bosons decaying into muons, an incredibly rare event that could deepen our understanding of how particles acquire mass. They also sharpened their ability to detect the even rarer Higgs decay into a Z boson and a photon—a process that might reveal hidden physics beyond the Standard Model.

The ATLAS Collaboration finds evidence of Higgs-boson decays to muons and improves sensitivity to Higgs-boson decays to a Z boson and a photon.

Since the discovery of the Higgs boson in 2012, physicists have made major strides in exploring its properties...

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