Constructed strain achieves record-high yield from methanol, advancing ecofriendly biomanufacturing. Researchers from Osaka Metropolitan University have discovered the ideal genetic “recipe” to turn yeast into a tiny yet powerful eco-friendly factory that converts methanol into D-lactic acid, a key compound used in biodegradable plastics and pharmaceuticals.

This approach could help reduce reliance on petroleum-based processes and contribute to more sustainable chemical production.

Lactic acid is widely used in food...

A terrifying glimpse at one potential fate of our Milky Way galaxy has come to light thanks to the discovery of a cosmic anomaly that challenges our understanding of the universe.

An international team of astronomers led by CHRIST University, Bangalore, found that a massive spiral galaxy almost 1 billion light-years away from Earth harbors a supermassive black hole billions of times the sun’s mass which is powering colossal radio jets stretching 6 million light-years across.

That is one o...

Using computational tools and virtual screening, researchers at the Center for Redox Processes in Biomedicine (Redoxoma) have identified new inhibitors of the enzyme human 15-lipoxygenase-2 (h15-LOX-2). This protein plays an important role in inflammatory and metabolic processes and contributes to cellular homeostasis.

The discovery, described in the Journal of Medicinal Chemistry, could open up new avenues for investigating the biological and pathological functions of the enzyme and provide promising candidates for the development of new drugs.

“Although h15-LOX-2 is a potential biological target, it’s scarcely been explored for this purpose...

So-called “memristors” consume extremely little power and behave similarly to brain cells. Researchers from Jülich, led by Ilia Valov, have now introduced novel memristive components that offer significant advantages over previous versions: they are more robust, function across a wider voltage range, and can operate in both analog and digital modes. These properties could help address the problem of “catastrophic forgetting,” where artificial neural networks abruptly forget previously learned information.

The problem of catastrophic forgetting occurs when deep neural networks are trained for a new task...