ITK is required for parasitic/viral infection-induced Tr1 cell development in vivo

By learning how a recently discovered immune cell works in the body, researchers hope to one day harness the cells to better treat allergies and infections, according to new Cornell University research. Type 1 regulatory (Tr1) cells are a type of regulatory immune cell that help suppress immune responses, including inflammation and tissue damage, but very few details were known about their development and function.

A new study with mice and humans, published in the journal Nature Communications, describes how an enzyme called ITK plays a crucial role in the development of Tr1 cells during an immune response...

MIT researchers have developed a new design system that catalogues the physical properties of a huge number of tiny cube clusters. These clusters can then serve as building blocks for larger printable objects. Credit: Computational Fabrication Group at MIT

Designing the microstructure of printed objects. Today’s 3D printers have a resolution of 600 dots per inch, ie they could pack a billion tiny cubes of different materials into a volume that measures just 1.67 cubic inches. Such precise control of printed objects’ microstructure gives designers commensurate control of the objects’ physical properties – eg. density or strength, or the way they deform when subjected to stresses...

Artist’s depiction of a neutron star. Credit Credit: NASA

Astronomers like to say we are the byproducts of stars, stellar furnaces that long ago fused hydrogen and helium into the elements needed for life through the process of stellar nucleosynthesis. As the late Carl Sagan once put it: “The nitrogen in our DNA, the calcium in our teeth, the iron in our blood, the carbon in our apple pies were made in the interiors of collapsing stars. We are made of star stuff.” But what about the heavier elements in the periodic chart, elements such as gold, platinum and uranium?

Astronomers believe most of these “r-process elements” – elements much heavier than iron – were created, either in the aftermath of the collapse of massive stars and the associated supernova explosions, or in the merging of b...

Astronomers have identified the oldest asteroid families and, by process of elimination, the oldest intact asteroids in the main belt. A team including SwRI scientists developed a technique to identify ancient asteroid families that have drifted apart. Asteroid surfaces heat up during the day (as illustrated by this image) and cool down at night, giving off radiation that can act as a sort of mini-thruster. This force can cause asteroids to drift widely over time, making it difficult to identify families of fragments leftover after asteroid collisions eons ago. Credit: Image Courtesy of NASA/GSFC

Discoveries include a void in the main belt and the oldest family of asteroids...