Nearly three-quarters of patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor’s genetic landscape, a new analysis finds.

More biomarker-based clinical trials will increase opportunities. A new analysis finds that nearly 3/4 of 500 patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor’s genetic landscape. The study suggests the value of next generation sequencing, a sophisticated method of evaluating the DNA and RNA of a tumor to help direct treatment.

A report on the first 500 patients with advanced solid tumors to go through the University of Michigan Comprehensive Cancer Center’s sequencing program found...

Photosystems (PS) I and II are large protein complexes that contain light-absorbing pigment molecules needed for photosynthesis. PS II captures energy from sunlight to extract electrons from water molecules, splitting water into oxygen and hydrogen ions (H+) and producing chemical energy in the form of ATP. PS I uses those electrons and H+ to reduce NADP+ (an electron-carrier molecule) to NADPH. The chemical energy contained in ATP and NADPH is then used in the light-independent reaction of photosynthesis to convert carbon dioxide to sugars.
Credit: Brookhaven National Laboratory

Photosynthesis in green plants converts solar energy to stored chemical energy by transforming atmospheric CO2 and water into sugar molecules that fuel plant growth...

1. A brown dwarf can give off some light, allowing scientists — professional or volunteer — to search for the object as it moves across the sky.
Chuck Carter and Gregg Hallinan/Caltech/NASA
2. This gif shows the ‘flipbook’ from which citizen scientists identified the new brown dwarf, marked with the red circle.
Credit: NASA

A new citizen-science tool released earlier this year to help astronomers pinpoint new worlds lurking in the outer reaches of our solar system has already led to a discovery: a brown dwarf a little more than 100 light years away from the Sun. Just 6 days after the launch of the Backyard Worlds: Planet 9 website in February, 4 different users alerted the science team to the curious object, whose presence has since been confirmed via an infrared telescope...

Sedimentary Signs of a Martian Lakebed (Shallow Part): This evenly layered rock imaged in 2014 by the Mastcam on NASA’s Curiosity Mars rover shows a pattern typical of a lake-floor sedimentary deposit near where flowing water entered a lake. Shallow and deep parts of an ancient Martian lake left different clues in mudstone formed from lakebed deposits. Credit: NASA/JPL-Caltech/MSSS

Water carried more oxygen at certain times, depths. A long-lasting lake on ancient Mars provided stable environmental conditions that differed significantly from one part of the lake to another, according to a comprehensive look at findings from the first three-and-a-half years of NASA’s Curiosity rover mission...