DNA Vaccine Protects against Toxic Proteins linked to Alzheimer’s

DNA vaccine protects against toxic proteins linked to Alzheimer's

UT Southwestern researchers have developed a DNA vaccine that helps the body protect against toxic proteins associated with Alzheimer’s disease. These images show amyloid plaque in the mouse brain using plasma containing anti-amyloid antibody from large mammals immunized with the vaccine. Credit: UT Southwestern

A new DNA vaccine when delivered to the skin prompts an immune response that produces antibodies to protect against toxic proteins associated with Alzheimer’s disease – without triggering severe brain swelling that earlier antibody treatments caused in some patients. Two studies from the Peter O’Donnell Jr. Brain Institute demonstrate in animals how a vaccine containing DNA of the toxic beta-amyloid protein elicits a different immune response that may be safe for humans...

Read More

Why our Brain Cells may Prevent us Burning Fat when we’re Dieting

A study carried out in mice may help explain why dieting can be an inefficient way to lose weight: key brain cells act as a trigger to prevent us burning calories when food is scarce.

A study carried out in mice may help explain why dieting can be an inefficient way to lose weight: key brain cells act as a trigger to prevent us burning calories when food is scarce.

A study carried out in mice may help explain why dieting can be an inefficient way to lose weight: key brain cells act as a trigger to prevent us burning calories when food is scarce. “Weight loss strategies are often inefficient because the body works like a thermostat and couples the amount of calories we burn to the amount of calories we eat,” says Dr Clémence Blouet from the Metabolic Research Laboratories at University of Cambridge. “When we eat less, our body compensates and burns fewer calories, which makes losing weight harder...

Read More

A Self-Healing Structural Color Hydrogel Inspired by Nature

A self-healing structural color hydrogel inspired by nature A set of self-healing hydrogel films with different structural colors. Credit: Yuanjin Zhao.

A self-healing structural color hydrogel inspired by nature A set of self-healing hydrogel films with different structural colors. Credit: Yuanjin Zhao.

A team of researchers at Southeast University in China has developed a self-healing structural hydrogel with a wide variety of applications. It has been noted for several years that one area where humanoid robots are lacking is skin tone—most robots have a pasty white complexion, which is both disturbing and likely to lead to social problems once robots become mainstream. Most artificial skin is not able to heal itself, which means that robots need skin replacement if it gets damaged or accidentally colored in undesirable ways. There is also the issue of colors fading...

Read More

Researchers find 1st compelling evidence of new property known as ‘Ferroelasticity’ in Perovskites

1, Schematic shows a perovskite sample (black) examined by the photothermal induced resonance technique. When the sample absorbs pulses of light (depicted as disks in purple cones), the sample expands rapidly, causing the cantilever of an atomic force microscope (AFM) to vibrate like a struck tuning fork. The cantilever’s motion, which is detected by reflecting the AFM laser light (red) off the AFM detector, provides a sensitive measure of the amount of light absorbed. Credit: NIST 2. Image recorded by an atomic force microscope reveals the topography of a polycrystalline sample of the perovskite, including the boundaries between crystals. Credit: NIST 3. Illustration shows that in response to an applied stress, such as bending, the boundaries of the ferroelastic domains (red and blue regions depict domains oriented in different directions) become bigger or smaller. Credit: NIST

1, Schematic shows a perovskite sample (black) examined by the photothermal induced resonance technique. When the sample absorbs pulses of light (depicted as disks in purple cones), the sample expands rapidly, causing the cantilever of an atomic force microscope (AFM) to vibrate like a struck tuning fork. The cantilever’s motion, which is detected by reflecting the AFM laser light (red) off the AFM detector, provides a sensitive measure of the amount of light absorbed.  2. Image recorded by an atomic force microscope reveals the topography of a polycrystalline sample of the perovskite, including the boundaries between crystals. 3...

Read More