Key Role for MicroRNA in Inflammatory Bowel Disease

Compared with a control (left), treatment with a miR-223 mimetic (right) reduces inflammation in mouse intestine. Credit: Neudecker et al., 2017

Compared with a control (left), treatment with a miR-223 mimetic (right) reduces inflammation in mouse intestine. Credit: Neudecker et al., 2017

An international team has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine. The study, “Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome,” shows that synthetic versions of this microRNA can reduce intestinal inflammation in mice and suggests a new therapeutic approach to treating patients with Crohn’s or ulcerative colitis.

Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, affects almost 2 million people in the US...

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Transistors that can Switch between 2 Stable Energy States

University of Illinois engineer Milton Feng and his team have introduced an upgrade to transistor lasers that could boost computer processor speeds. Credit: Photo by L. Brian Stauffer

University of Illinois engineer Milton Feng and his team have introduced an upgrade to transistor lasers that could boost computer processor speeds. Credit: Photo by L. Brian Stauffer

Engineers are unveiling an upgrade to the transistor laser that could be used to boost computer processor speeds – the formation of two stable energy states and the ability to switch between them quickly. Modern computers are limited by a delay formed as electrons travel through the tiny wires and switches on a computer chip. To overcome this electronic backlog, engineers would like to develop a computer that transmits information using light, in addition to electricity, because light travels faster than electricity.

Having two stable energy states, or bistability, within a transistor allows the device to for...

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Quartz Powder for the Battery of the Future

PSI researcher Claire Villevieille, head of the Battery Materials Group, at the instrument for X-ray diffraction. Credit: Paul Scherrer Institute/Markus Fischer

PSI researcher Claire Villevieille, head of the Battery Materials Group, at the instrument for X-ray diffraction. Credit: Paul Scherrer Institute/Markus Fischer

PSI, Switzerland and Université Grenoble Alpes (France) researchers have developed a method that could enable a breakthrough for the lithium-sulphur battery. In theory, these batteries can deliver considerably more energy than today’s conventional lithium-ion batteries, but current prototypes show a distinct loss of capacity after just a few charging cycles. So they are not yet fit for widespread use, for instance in electric vehicles. With their new method, the researchers were able to gain crucial insights into how the rapid capacity loss occurs...

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Space Weather Model Simulates Solar Storms from Nowhere

Watch the evolution of a stealth CME in this simulation. Differential rotation creates a twisted mass of magnetic fields on the sun, which then pinches off and speeds out into space. The image of the sun is from NASA's STEREO. Colored lines depict magnetic field lines, and the different colors indicate in which layers of the sun's atmosphere they originate. The white lines become stressed and form a coil, eventually erupting from the sun. Credit: NASA's Goddard Space Flight Center/ARMS/Joy Ng, producer

Watch the evolution of a stealth CME in this simulation. Differential rotation creates a twisted mass of magnetic fields on the sun, which then pinches off and speeds out into space. The image of the sun is from NASA’s STEREO. Colored lines depict magnetic field lines, and the different colors indicate in which layers of the sun’s atmosphere they originate. The white lines become stressed and form a coil, eventually erupting from the sun. Credit: NASA’s Goddard Space Flight Center/ARMS/Joy Ng, producer

A kind of solar storm has puzzled scientists for its lack of typical warning signs: They seem to come from nowhere, and scientists call them stealth CMEs. Now, scientists have developed a model simulating their evolution...

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