The Role of a Telomere Capping Complex in Cancer revealed

X-ray crystal structure of the human POT1-TPP1 telomere maintenance complex. POT1 is shown in salmon and TPP1 in lime color. Credit: The Wistar Institute

X-ray crystal structure of the human POT1-TPP1 telomere maintenance complex. POT1 is shown in salmon and TPP1 in lime color. Credit: The Wistar Institute

Scientists at The Wistar Institute have unveiled part of the protein complex that protects telomeres – the ends of our chromosomes. The study explains how a group of genetic mutations associated with this protein complex contributes to various cancers. Telomeres are the protective structures at the end of chromosomes and are essential for the faithful replication and protection of our genome. Defects in telomere function can lead to genomic instability in cancer, while the gradual shortening of telomeres is associated with the aging of human cells...

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New Technology can Detect Tiny Ovarian Tumors

A high-magnification micrograph of an ovarian clear cell carcinoma. The images show, focally, the characteristic clear cells with prominent nucleoli and the typical hyaline globules. A high-magnification micrograph of an ovarian clear cell carcinoma. The images show, focally, the characteristic clear cells with prominent nucleoli and the typical hyaline globules. Image: Nephron/CC BY-SA 3.0

A high-magnification micrograph of an ovarian clear cell carcinoma. The images show, focally, the characteristic clear cells with prominent nucleoli and the typical hyaline globules. A high-magnification micrograph of an ovarian clear cell carcinoma. The images show, focally, the characteristic clear cells with prominent nucleoli and the typical hyaline globules. Image: Nephron/CC BY-SA 3.0

‘Synthetic biomarkers’ could be used to diagnose ovarian cancer months earlier than now possible. Most ovarian cancer is diagnosed at such late stages that patients’ survival rates are poor. However, if the cancer is detected earlier, 5-year survival rates can be greater than 90%...

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Inkjet Process to Print Flexible Touchscreens Cost-Efficiently

Printed, flexible touchscreen. Credit: INM

Printed, flexible touchscreen. Credit: INM

Flexible smart phones are desirable for a lot of users. Up to now the displays of the innumerable phones and pods are rigid and do not yield to the anatomical forms adopted by the people carrying them. By now it is no longer any secret that the big players in the industry are working on flexible displays. INM – Leibniz Institute for New Materials shows, how they might become reality in the near future: At this year’s Hannover Messe, INM will be presenting suitable coatings for cost-efficient inkjet processes on 24 April to 28 April.

INM will be demonstrating flexible touch screens, which are produced by printing recently developed nanoparticle inks on thin plastic foils...

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Diamonds Coupled using Quantum Physics

Zwei schwarze Diamanten auf einem supraleitenden Chip (12x4mm). Die Geschwungene Linie ist ein Resonator, der die beiden Diamanten koppelt.

Two black diamonds on a superconducting chip (12x4mm). The wiggly line is a resonator, coupling the two diamonds.

Atomic defects in diamonds can be used as quantum memories. Researchers at TU Wien have been studying the quantum properties of such diamonds, but only now have they succeeded in coupling the specific defects in two such diamonds with one another. This is an important prerequisite for the development of new applications, such as highly sensitive sensors and switches for quantum computers.

“Unfortunately, quantum states are very fragile and decay very quickly,” explains Johannes Majer, head of the hybrid quantum research group, Institute of Atomic and Subatomic Physics at TU Wien...

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