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    Unraveling the functional diversity of Longevity gene SIRT1

    March 28, 2017, Categories  Health/Medical, Biology/Biotechnology

    Highlights •SIRT1-ΔE2 is a tissue-restricted splice variant of SIRT1 •SIRT1-FL/SIRT1-ΔE2 are indistinguishable vis-à-vis intrinsic catalytic activities •The conserved exon 2 (E2) domain may act to tether substrates •E2 encodes molecular specificity of interactions and functions

    Highlights •SIRT1-ΔE2 is a tissue-restricted splice variant of SIRT1 •SIRT1-FL/SIRT1-ΔE2 are indistinguishable vis-à-vis intrinsic catalytic activities •The conserved exon 2 (E2) domain may act to tether substrates •E2 encodes molecular specificity of interactions and functions

    Two alternate forms of SIRT1 leads to the discovery of how molecular specificity is encoded. While the search for elixir of life has captivated human imagination for millennia, researchers around the world have put in efforts to extend healthy lifespan and reduce the burden of morbid diseases in an increasingly aging population...

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    Vitamin D decreases risk of Cancer, new study suggests

    March 28, 2017, Categories  Health/Medical, Biology/Biotechnology

    vit D pathway

    vit D pathway

    Increasing vitamin D levels may lower risk for developing cancer, according to a study conducted by Creighton University with cooperation from the University of California San Diego. The results of the study were released today in the Journal of the American Medical Association. The study, funded by the National Institutes of Health, is a randomized clinical trial of the effects of vitamin D supplementation on all types of cancer combined.

    en 55 years and older from 31 counties in Nebraska. Participants were randomly assigned to take either 2000 international units (IU) of vitamin D3 and 1500 mg. of calcium or identical placebos daily for 4 years...

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    Secret of Nanomaterial that makes Harvesting Sunlight easier

    March 28, 2017, Categories  Physics, Technology/Electronics, Chemistry/Nanotechnology

    Scheme of the local surface chemistry modification and AuNPs tracking approach.

    Scheme of the local surface chemistry modification and AuNPs tracking approach. (a) Ag nanoantennas were modified overnight with 1 mM ethanolic solution of 4-NTP. Several ethanol/water washing steps were performed on each sample. (b) 4-NTP-coated antennas were immersed in 0.1 M HCl solution and illuminated for different times at their LSPR wavelength (633 nm) with a power density of 1 W cm−2. Samples were rinsed with water and immediately dipped in the activated AuNP suspension. (c) AuNPs (15 nm) coated with 11-mercaptoundecanoic acid (MUA) as a capping layer were suspended in HEPES buffer and mixed with 1 mM EDC and 1 mM NHS, and left to react for 30 min followed by two purification centrifugation steps...

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    Artificial Materials created Atom-by-Atom

    March 28, 2017, Categories  Physics, Technology/Electronics, Chemistry/Nanotechnology

    The tip of a scanning tunnelling microscope (STM) above chlorine atoms that have been deliberately moved. By moving individual atoms under their microscope, scientists were able to arrange vacancies in a single layer of chlorine atoms and create atomic lattices with a predetermined electrical response. Photo Ella Maru Studio.

    The tip of a scanning tunnelling microscope (STM) above chlorine atoms that have been deliberately moved. By moving individual atoms under their microscope, scientists were able to arrange vacancies in a single layer of chlorine atoms and create atomic lattices with a predetermined electrical response. Photo Ella Maru Studio.

    Possibility to arrange the atoms precisely bring designer quantum materials closer to reality. Aalto University researchers have manufactured artificial materials with engineered electronic properties. By moving individual atoms under their microscope, they were able to create atomic lattices with a predetermined electrical response. The possibility to precisely arrange the atoms on a sample bring ‘designer quantum materials’ one step closer to reality...

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