Top, from left: Dr. Wan Hee Yoon and Dr. Hugo Bellen. Bottom, from left: Dr. James R. Lupski and Dr. Michael F. Wangler.

An international team has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria – the energy-producing factory of the cell – and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans. Working with the fruit fly, an experimental animal model in the lab, the scientists found a mechanism by which misregulation of mitochondrial function leads to neurodegeneration. The results appear in Neuron.

“In our research we look for genes whose loss of function results in deterioration of neurological functions in the fruit fly Drosophila melanogaster,” said Dr...

Laser light generates and probes sound waves in the core of a fiber optic waveguide. Credit: Yale University

Yale scientists have shown how to enhance the lifetime of sound waves traveling through glass—the material at the heart of fiber optic technologies. Everyday experience tells us that glass (silica) is highly transparent. In fact, silica is one of the most transparent materials on earth. Light can propagate for tens of kilometers in silica before it experiences any appreciable weakening. This transparency, combined with glass’ formability and low cost, is why glass is used in so many of the fiber-optic technologies that shape the information age.

Yet silica also has a mysterious side. At room temperature, silica is an excellent acoustic material...

Scanning transmission electron microscope image of a nickel-platinum composite material created at The Ohio State University. At left, the image is overlaid with false-color maps of elements in the material, including platinum (red), nickel (green) and oxygen (blue). Credit: Imaging by Isabel Boona, OSU Center for Electron Microscopy and Analysis; Left image prepared by Renee Ripley. Courtesy of The Ohio State University

The same researchers who pioneered the use of a quantum mechanical effect to convert heat into electricity have figured out how to make their technique work in a form more suitable to industry...

A fully packaged device for trapping and manipulating single electrons and photons. A series of on-chip electrodes (lower left and upper right) lead to the formation of a double quantum dot that confines a single electron below the surface of the chip. The photon, which is free to move within the full 7-millimeter span of the cavity, exchanges quantum information with the electron inside the double quantum dot. (Photo courtesy of the Jason Petta research group, Department of Physics)

In a step that brings silicon-based quantum computers closer to reality, researchers at Princeton University have built a device in which a single electron can pass its quantum information to a particle of light...