While investigating the FGF21-oxytocin-dopamine system, a mechanism that regulates sugar appetite, a team of researchers at Kyoto University noticed reports suggesting that the protein FGF21 may regulate alcohol ingestion.

The team’s original aim had been to address sugar appetite in lifestyle-related diseases, but since alcohol is a fermented product of sugar, they speculated that perhaps the body contains a system that recognizes both alcohol and sugar as the same entity.

Alcohol consumption and intervention challenges
Excessive alcohol consumption is a major global health issue, and effective countermeasures for prevention and treatment are limited...

X-ray tomography is a powerful tool that enables scientists and engineers to peer inside of objects in 3D, including computer chips and advanced battery materials, without performing anything invasive. It’s the same basic method behind medical CT scans.

Scientists or technicians capture X-ray images as an object is rotated, and then advanced software mathematically reconstructs the object’s 3D internal structure...

At half the size of Earth and one-tenth its mass, Mars is a featherweight as far as planets go. Yet new research reveals the extent to which Mars is quietly tugging on Earth’s orbit and shaping the cycles that drive long-term climate patterns here, including ice ages.

The study is published in the journal Publications of the Astronomical Society of the Pacific.

Stephen Kane, a professor of planetary astrophysics at UC Riverside, began this project with doubts about recent studies tying Earth’s ancient climate patterns to gravitational nudges from Mars. These studies suggest that sediment layers on the ocean floor reflect climate cycles influenced by the red planet despite its distance from Earth and small size.

“I knew Mars had some effect on Earth, but I assumed it was tiny,...

Multiple sclerosis (MS) is a chronic neurological disease characterized by nerve damage and consequent impairments in vision, movement, balance and mental function. In MS, the immune system mistakenly starts attacking myelin, the protective sheath that surrounds axons (i.e., nerve fibers) in the brain, spinal cord and optic nerves.

Macrophages, immune cells responsible for detecting damaged cells, germs or other debris in the central nervous system (CNS) and eliminating them, have been found to play a key role in MS...