New insights into sleep uncover mechanisms with broad implications for boosting brainpower

Credit: AI-generated image

Discovery suggests broad implications for giving brain a boost. While it’s well known that sleep enhances cognitive performance, the underlying neural mechanisms, particularly those related to nonrapid eye movement (NREM) sleep, remain largely unexplored. A new study by a team of researchers at Rice University and Houston Methodist’s Center for Neural Systems Restoration and Weill Cornell Medical College, coordinated by Rice’s Valentin Dragoi, has nonetheless uncovered a key mechanism by which sleep enhances neuronal and behavioral performance, potentially changing our fundamental understanding of how sleep boosts brainpower.

The research, published in Science, reveals how NREM sleep — the lighter sleep one experiences when taking a nap, for example — fost...

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Discovery of van Hove Singularities could Lead to Novel Materials with Desirable Quantum Properties

Discovery could lead to novel materials with desirable quantum properties
The electronic topology in the chiral fermion conductors RhSi and CoSi. Credit: Nature Physics (2023). DOI: 10.1038/s41567-022-01892-6

Strong interactions between subatomic particles like electrons occur when they are at a specific energy level known as the van Hove singularity. These interactions give rise to unusual properties in quantum materials, such as superconductivity at high temperatures, potentially ushering in exciting technologies of tomorrow.

Research suggests topological materials that allow electrons to flow only on their surface to be promising quantum materials. However, the quantum properties of these materials remain relatively unexplored.

A study co-led by Nanyang Asst Prof Chang Guoqing of NTU’s School of Physical and Mathematical Sciences identified two ty...

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The Dark Energy Pushing our Universe Apart may not be what it seems, scientists say

The dark energy pushing our universe apart may not be what it seems, scientists say
This Dec. 14, 2023 image made available by NOIRLab shows meteors from the Geminid meteor shower streaking across the sky above the Nicholas U. Mayall Telescope at Kitt Peak National Observatory (KPNO), a Program of NSF’s NOIRLab, in Tucson, Ariz. Credit: NSF’s NOIRLab via AP

Distant, ancient galaxies are giving scientists more hints that a mysterious force called dark energy may not be what they thought.

Astronomers know that the universe is being pushed apart at an accelerating rate and they have puzzled for decades over what could possibly be speeding everything up. They theorize that a powerful, constant force is at play, one that fits nicely with the main mathematical model that describes how the universe behaves...

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Scientists discover ‘Toolkit’ to Fix DNA Breaks Associated with Aging, Cancer and Motor Neuron Disease

Experts discover toolkit to repair DNA breaks associated with aging, cancer and motor neuron disease
TEX264 acts at replication forks. Credit: Nature Communications (2020). DOI: 10.1038/s41467-020-15000-w

A new “toolkit” to repair damaged DNA that can lead to aging, cancer and motor neuron disease (MND) has been discovered by scientists at the Universities of Sheffield and Oxford.

Published in Nature Communications, the research shows that a protein called TEX264, together with other enzymes, is able to recognize and “eat” toxic proteins that can stick to DNA and cause it to become damaged. An accumulation of broken, damaged DNA can cause cellular aging, cancer and neurological diseases such as MND.

Until now, ways of repairing this sort of DNA damage have been poorly understood, but scientists hope to exploit this novel repair toolkit of proteins to protect us from aging, can...

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