Estrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a variety of physiological processes. At Baylor College of Medicine, Louisiana State University and collaborating institutions, researchers discovered that estrogen’s fast actions are mediated by the coupling of the estrogen receptor-alpha (ER-alpha) with an ion channel protein called Clic1.

Clic1 controls the fast flux of electrically charged chloride ions through the cell membrane, which neurons use for receiving, conducting and transmitting signals. The researchers propose that interacting with the ER-alpha-Clic1 complex enables estrogen to trigger fast neuronal responses through Clic1 ion currents. The study appears in Science Advances.

“Estrogen can act in the brain to reg...

Researchers at McGill University have made a significant advance in the development of all-solid-state lithium batteries, which are being pursued as the next step in electric vehicle (EV) battery technology.

By addressing a long-standing issue with battery performance, this innovation could pave the way for safer, longer-lasting EVs. The findings are published in the journal Cell Reports Physical Science.

The challenge lies in the resistance that occurs where the ceramic electrolyte meets the electrodes. This makes the battery less efficient and reduces how much energy it can deliver...

Inspired by the half-human, half-horse creatures that are part of Ancient Greek mythology, the field of astronomy has its own kind of centaurs: distant objects orbiting the sun between Jupiter and Neptune. NASA’s James Webb Space Telescope has mapped the gases spewing from one of these objects, suggesting a varied composition and providing new insights into the formation and evolution of the solar system.

Centaurs are former trans-Neptunian objects that have been moved inside Neptune’s orbit by subtle gravitational influences of the planets in the last few million years, and may eventually become short-period comets...

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion of the natural sweetener thaumatin. In a cellular test system, the peptides are able to stimulate the acid secretion of human stomach cells and influence inflammatory reactions. “Our research helps to elucidate the health effects of the plant protein, which is widely used as a sweetener,” says Veronika Somoza, head of the study and director of the Leibniz Institute.

Veronika Somoza’s team is researching, among other things, how bitter-tasting food compounds influence the metabolism of s...