Cirrus Therapeutics, the University of Bristol, and London’s Global University Institute of Ophthalmology have discovered a new treatment for age-related macular degeneration (AMD), the leading cause of vision loss among older adults.

Featured on the cover of the journal Science Translational Medicine, this research reveals that boosting a specific protein, IRAK-M, in retinal cells could offer a new and highly effective therapy for AMD.

AMD can severely impact a person’s vision. Patients suffering from AMD often start with blurred vision or seeing a black dot in their central vision, which can ultimately expand to the point where there is no useful central vision...

With the rapid advancement of artificial intelligence, unmanned systems such as autonomous driving and embodied intelligence are continuously being promoted and applied in real-world scenarios, leading to a new wave of technological revolution and industrial transformation. Visual perception, a core means of information acquisition, plays a crucial role in these intelligent systems. However, achieving efficient, precise, and robust visual perception in dynamic, diverse, and unpredictable environments remains an open challenge.

In open-world scenarios, intelligent systems must not only process vast amounts of data but also handle various extreme events, such as sudden dangers, drastic light changes at tunnel entrances, and strong flash interference at night in driving scenarios.

Exoplanets are common in our galaxy, and some even orbit in the so-called habitable zone of their star. NASA’s James Webb Space Telescope has been busy observing a few of these small, potentially habitable planets, and astronomers are now hard at work analyzing Webb data. We invite Drs...

Scientists at Duke-NUS Medical School have identified how the first domino falls after a person encounters an allergen, such as peanuts, shellfish, pollen or dustmites. Their discovery, published in the April issue of Nature Immunology, could herald the development of drugs to prevent these severe reactions.

It is well established that when mast cells, a type of immune cell, mistake a harmless substance, such as peanuts or dust mites, as a threat, they release an immediate first wave of bioactive chemicals against the perceived threat...