Common Cold Virus Linked to Potentially Fatal Blood Clotting Disorder

Image: Red-colored region depicts region on platelet factor 4 (PF4) molecule recognized by VITT-like antibodies obtained from patient 2 (adult). Credit: Mercy Daka (co-author) and Dr. Ishac Nazy (co-author)

A new observation suggests that a life-threatening blood clotting disorder can be caused by an infection with adenovirus, one of the most common respiratory viruses in pediatric and adult patients.

Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop throughout the body, termed thrombocytopenia.

After a robust clinical and research collaboration, Stephan Moll, MD, and Jacquelyn Baskin-Miller, MD, both in the UN...

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Simple Ballpoint Pen can Write Custom LEDs

Handwriting LEDs

The invention of the printing press revolutionized duplication of the written word, giving the hands of tired scribes a break and making written material more accessible. A similar breakthrough has happened in reverse in the McKelvey School of Engineering at Washington University in St. Louis.

Researchers working with Chuan Wang, associate professor of electrical & systems engineering, have developed ink pens that allow individuals to handwrite flexible, stretchable optoelectronic devices on everyday materials including paper, textiles, rubber, plastics and 3D objects. Flexible optoelectronics for emitting and detecting light, which are already found in everyday objects like smartphones and fitness trackers, can bend, fold and flex while maintaining functionality.

In a paper pub...

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Stellar Surf’s up: Monster Waves as tall as Three Suns are Crashing upon a Colossal Star

Artist conception of the system, where the smaller star induces breaking surface waves in the more massive companion.
Credit: Melissa Weiss, CfA

An extreme star system is giving new meaning to the phrase “surf’s up.”

The star system intrigued researchers because it is the most dramatic “heartbeat star” on record. Now new models have revealed that titanic waves, generated by tides, are repeatedly breaking on one of the stars in the system—the first time this phenomenon has ever been seen on a star.

Heartbeat stars are stars in close pairs that periodically pulse in brightness, like the rhythm of a beating heart on an EKG machine. The stars in heartbeat systems loop through elongated oval orbits. Whenever they swing close together, the stars’ gravities generate tides—just as the Moon creates ocean tides on Earth...

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A New Mechanism Encouraging the Brain to Self-Repair After an Ischemic Stroke

Lipid metabolism triggering brain-autonomous neural repair after ischemic stroke
The neurons around an injured brain region will play major roles in promoting functional recovery through nervous system development, synapse organization, and remyelination; however, the molecular mechanisms triggering such a broad range of neural repair after brain injury remained unknown. Our study demonstrated that the secretion of PLA2G2E from perilesional neurons with ischemic stress generated DGLA and 15-HETrE, which triggered these recovery processes through the neuronal Padi4-dependent induction of cluster formation associated with neural repair after ischemic brain injury.

Partial recovery after ischemic stroke is possible, but the mechanisms involved in this process remain unclear...

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