Tropical Plant Native to China Reveals Antiobesity Potential

Dried Mallotus furetianus leaves

Mallotus furetianus, a tropical plant of the Euphorbiaceae family, native to Hainan Island, China.

Credit: Akiko Kojima, Osaka Metropolitan University

Scientists discover that Mallotus furetianus, native to Hainan Island, China, has antiobesity effects. Scientists tested the antiobesity effects of Mallotus furetianus extract native to Hainan Island, China, using obesity model mice. As a result, body weight and adipose tissue weight of obesity model mice were significantly reduced by the intake of Mallotus furetianus extract. Fatty liver was suppressed and adipocyte size reduction in adipose tissue was observed...

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Self-supervised AI Learns Physics to Reconstruct Microscopic Images from Holograms

GedankenNet 2
Ozcan Research Lab/UCLA
Images showing the training and testing of UCLA-developed AI-powered GedankenNet using simulated holograms generated from random images in reconstructing microscopic images of various human tissue sections and Pap smears. Scale bar: 50 μm (millionth of a meter)

Advance uses thought experiments, instead of real data, to expedite learning. Researchers from the UCLA Samueli School of Engineering have unveiled an artificial intelligence-based model for computational imaging and microscopy without training with experimental objects or real data.

In a recent paper published in Nature Machine Intelligence, UCLA’s Volgenau Professor for Engineering Innovation Aydogan Ozcan and his research team introduced a self-supervised AI model nicknamed GedankenNet that learns f...

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Hubble Glimpses Globular Cluster NGC 6652

A spherical cluster of stars with a bright core, and stars spread out to the edges gradually giving way to an empty, dark background. A few stars with cross-shaped diffraction spikes appear larger and stand out in front.
Text credit: European Space Agency (ESA)
Image credit: ESA/Hubble & NASA, A. Sarajedini, G. Piotto

The glittering, glitzy contents of the globular cluster NGC 6652 sparkle in this star-studded image from the NASA/ESA Hubble Space Telescope. The core of the cluster is suffused with the pale blue light of countless stars, and a handful of particularly bright foreground stars are adorned with crisscrossing diffraction spikes. NGC 6652 lies in our own Milky Way galaxy in the constellation Sagittarius, just under 30,000 light-years from Earth and only 6,500 light-years from the galactic center.

Globular clusters are stable, tightly gravitationally bound clusters containing anywhere from tens of thousands to millions of stars...

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‘Spider-like’ Mitochondrial Structure Initiates Cell-wide Stress Response

“Spider-like” mitochondrial structure initiates cell-wide stress response
A structural depiction of a mitochondrial protein structure that initiates a cell-wide stress response. Using electron microscopy, Scripps Research scientists showed that this protein complex is made up of eight identical fragments of a protein called DELE1 that bind together into a highly symmetrical cylindrical. Credit: Jie Yang, Scripps Research

Often referred to as the “powerhouses of the cell,” mitochondria are well known for their role as energy suppliers, but these organelles are also critical for maintaining our overall health. Mitochondrial stress is associated with aging and age-related diseases, including neurodegeneration, but there has been a limited understanding of the cellular mechanisms behind this mitochondrial stress signaling...

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