First breathing ‘lung-on-chip’ developed using genetically identical cells

lung
Credit: Pixabay/CC0 Public Domain

Researchers at the Francis Crick Institute and AlveoliX have developed the first human lung-on-chip model using stem cells taken from only one person. These chips simulate breathing motions and lung disease in an individual, holding promise for testing treatments for infections like tuberculosis (TB) and delivering personalized medicine.

The research is published in the journal Science Advances.

Air sacs in the lungs called alveoli are the essential site of gas exchange and also an important barrier against inhaled viruses and bacteria that cause respiratory diseases like flu or TB.

Researchers have been working to recreate the battle between human cells and bacteria in the lab by building a lung-on-a-chip: small units of human lung on a plast...

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Tiny tech, big AI power: What are 2-nanometer chips?

Only a few companies are able to produce 2-nanometre chips, including Taiwan's TSMC, which dominates the industry
Only a few companies are able to produce 2-nanometer chips, including Taiwan’s TSMC, which dominates the industry.

Taiwan’s world-leading microchip manufacturer TSMC says it has started mass producing next-generation “2-nanometer” chips.

AFP looks at what that means, and why it’s important:

What can they do?
The computing power of chips has increased dramatically over the decades as makers cram them with more microscopic electronic components.

That has brought huge technological leaps to everything from smartphones to cars, as well as the advent of artificial intelligence tools like ChatGPT.

Advanced 2-nanometer (2nm) chips perform better and are more energy-efficient than past types, and are structured differently to house even more of the key components known as transistor...

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Searching for light dark matter by tracking its direction with quantum sensors

dark matter
Credit: Scott Lord from Pexels

Dark matter is an elusive type of matter that does not emit, absorb or reflect light, interacting very weakly with ordinary matter. These characteristics make it impossible to detect using conventional technologies used by physicists to study matter particles.

As it has never been observed before, the exact composition of dark matter remains unknown. One proposed theory is that this elusive type of matter is comprised of light particles with very small masses, below 1 eV (electronvolt), which behave more like waves than particles.

Researchers at the University of Tokyo and Chuo University recently explored the possibility of searching for sub-GeV dark matter using quantum sensors, advanced systems that rely on quantum mechanical effects to detect ex...

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Flu is rising rapidly, driven by a new variant. Here’s what to know

Flu is rising rapidly, driven by a new variant. Here's what to know
A certified medical assistant holds a syringe for a flu vaccine at a clinic in Seattle, on Wednesday, Sept. 10, 2025. Credit: AP Photo/Lindsey Wasson, File

Flu is rising rapidly across the U.S., driven by a new variant of the virus—and cases are expected to keep growing with holiday travel.

That variant, known as “subclade K,” led to early outbreaks in the United Kingdom, Japan and Canada. In the U.S., flu typically begins its winter march in December. On Tuesday, the Centers for Disease Control and Prevention reported high or very high levels of illness in more than half the states.

The CDC estimated there have been at least 7.5 million illnesses, 81,000 hospitalizations and 3,100 deaths from flu so far this season...

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