Scientists working in the School of Biochemistry and Immunology in the Trinity Biomedical Sciences Institute at Trinity College Dublin have made an important breakthrough in understanding what goes wrong in our bodies during the progression of inflammatory diseases and – in doing so – unearthed a potential new therapeutic target.

The scientists have found that an enzyme called Fumarate Hydratase is repressed in macrophages, a frontline inflammatory cell type implicated in a range of diseases including Lupus, Arthritis, Sepsis and COVID-19.

Professor Luke O’Neill, Professor of Biochemistry at Trinity is the lead author of the research article that has just been published in leading international journal, Nature. He said:

“No-one has made a link from Fumarate Hydratase to infla...

As the evolution of standard microchips is coming to an end, scientists are looking for a revolution. The big challenges are to design chips that are more energy efficient and to design devices that combine memory and logic (memristors). Materials scientists from the University of Groningen, the Netherlands, describe in two papers how complex oxides can be used to create very energy-efficient magneto-electric spin-orbit (MESO) devices and memristive devices with reduced dimensions.

The development of classic silicon-based computers is approaching its limits...

As tragic as it is, engulfment of a planetary object by its stellar parent is a common scenario throughout the universe. But it doesn’t have to end in doom. A team of astrophysicists have used computer simulations to discover that planets can not only survive when their star eats them, but they can also drive its future evolution.

Models of the formation of planetary systems have shown that many planets often end up being consumed by their parent star. It’s simply a matter of orbital dynamics. Random interactions among newly forming planets and the protoplanetary disk that surrounds a young star can send planets on chaotic trajectories. Some of those trajectories end up driving the planet out of the system altogether, while other trajectories send them hurdling into the star.

An...

Researchers at Universidad Carlos III de Madrid (UC3M) have created software and hardware for a 4D printer with applications in the biomedical field. In addition to 3D printing, this machine allows for controlling extra functions: programming the material’s response so that shape-changing occurs under external magnetic field, or changes in its electric properties develops under mechanical deformation...