Published in Aging Cell, the findings show that animals treated with rilmenidine, currently used to treat hypertension, at young and older ages increases lifespan and improves health markers, mimicking the effects of caloric restriction.

They also demonstrate that the healthspan and lifespan benefits of rilmenidine treatment in the roundworm C. elegans are mediated by the I1-imidazoline receptor nish-1, identifying this receptor as a potential longevity target.

Unlike other drugs previously studied for this purpose by the researchers, the widely-prescribed, oral antihypertensive rilmenidine has potential for future translatability to humans as side-effects are rare and non-severe.

To date, a caloric restriction diet has been considered the most robust anti-aging intervention,...

Per- and polyfluoroalkyl substances (PFAS) are potentially harmful substances known as “forever chemicals” because they are so difficult to destroy. One emerging technique to degrade PFAS involves forcefully grinding them with metal balls in a moving container, but this technique can require corrosive additives. Now, in Environmental Science & Technology Letters, researchers report a new type of additive for “ball milling” that completely breaks down PFAS at ambient temperature and pressure.

Solid PFAS contamination is an ongoing issue for soil near waste sites, manufacturing sites, and facilities that frequently use firefighting foam. Currently, the U.S...

An international team including Southwest Research Institute, Leiden University and NASA used observations from the James Webb Space Telescope (JWST) to achieve the darkest ever view of a dense interstellar cloud...

Traumatic injury to the brain, spinal cord and optic nerve in the central nervous system are the leading cause of disability and the second leading cause of d...